Science Briefing · Jul 13, 2026
TRIM3 and the Ubiquitin Checkpoint: Reframing PD-L1 Stability in Non-small Cell Lung Cancer
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This study identifies TRIM3 as a critical E3 ubiquitin ligase that regulates PD-L1 protein stability in non-small cell lung cancer (NSCLC), directly linking ubiquitin-mediated degradation to immune c…
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