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Polytechnic Journal

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Explainable AI Framework for Stage-Specific Drug Doses Prediction in Chronic Kidney Disease: A Multi-Algorithm Comparison with Adverse Event Prediction

Chronic Kidney Disease (CKD) affects medication dose safety due to altered pharmacokinetics. Current clinical decision support systems lack stage-specific personalization and explainability. Therefore, this study aimed to identify the appropriate medications and doses for chronic kidney disease using machine learning algorithms by comparing the methods. This study is divided into two phases. Phase…

A DFT study of Mg/Ti Fluorites-Structure Materials: Optoelectronic, Photocatalysis, and Hydrogen storage applications

This study employs density functional theory (DFT) to investigate the fluorite-derived tetragonal hydride MgTiH 4 , highlighting its multifunctionality for energy-related applications. Structural optimization reveals lattice constants of a = b = 3.15 Å and c = 4.70 Å, with a unit cell volume of 46.59 Å 3 and a high bulk modulus of 114.21 GPa, indicating mechanical robustness. Compared to its MgTiH…

Mechanisms of Vascular Acetylcholine Reactivity in Cardiac Hypertrophy: The Role of Calcium Channels and Endothelial PI3K/AKT/eNOS Signaling in Rats

Cardiac hypertrophy alters vascular function and promotes myocardial damage via oxidative stress and inflammation, with calcium channels and the PI3K/AKT/eNOS signalling pathway being pivotal in vascular reactivity. Nonetheless, their precise role in acetylcholine (ACh)-mediated vascular responses during hypertrophy remains little elucidated. The study aims to investigate calcium channel functions…

Snail-shell-derived biochar for the adsorption of petroleum pollutants from wastewater: Perspective from computational studies

Para-chlorophenols (PCPs) are toxic and persistent, chlorinated aromatics that are prevalent in industrial and petroleum-contaminated wastewater, which has serious environmental and health impacts because of their bioaccumulative and recalcitrant properties. The study aims to design and test chemically activated snail shell biochars (SSB) as an effective PCP remedial material, combining the…

Fabrication of WS₂ Thin Films via Spray Pyrolysis with Comprehensive Structural, Electrical, and Chemoresistive Analyses toward NO₂ Detection

Nanostructured metal sulphides are gaining attention as potential materials for resistive chemical sensors due to their high electrical conductivity and chemical stability compared to metal oxides. Among these, tungsten disulfide (WS₂), a transition metal dichalcogenide (TMD), stands out because of its distinctive electrical, optical, and mechanical properties. In this study, WS₂ thin films were…

Continuous Light and Pinealectomy: Two Models of Melatonin Deficiency Revealing Distinct Interactions with Vitamin D Deficiency on Blood Parameters

Modern lifestyles reduce sunlight exposure and increase artificial light at night, potentially promoting vitamin D deficiency (VDD) and melatonin (MEL) suppression. The two hormones regulate immunity, erythropoiesis, and platelet (PLT) indices, but their combined hematological effects are not well characterized. We investigated the independent and combined effects of VDD and MEL deficiency on…

Petroleum Potential of the Middle–Late Jurassic Source Rocks (Sargelu and Naokelekan Formations) in the Kurdistan Region, Northern Iraq.

This study evaluates the petroleum generating potential of the Middle-Late Jurassic Sargelu and Naokelekan Formations across distinct tectonic zones in the Kurdistan Region, Iraq. Source rock quality is assessed through geochemical analyses of organic matter (OM) quantity, type, thermal maturity, and key factors influencing hydro-carbon generation. Rock-Eval pyrolysis was performed on outcrop…

Characterization of Physical and Structural Properties in a Quaternary Li2O-B2O3-Bi2O3-V2O5 Glass System

Borate-based glasses modified with alkali oxides are of considerable interest due to their tunable structural and optical properties, which are important for optical and energy storage applications. In this work, glasses with a novel nominal composition of xLi2O-(75-x) B2O3—20Bi2O3—5V2O5, in which (x ¼ 5, 10, 15, 20, 25 mol %) were produced using the traditional melt-quenching technique to…

Enhancing the Capability of A Hybrid TWDM/PON Using Waveguide-Integrated Si/2D Material-Based Photodetector with the Most Suitable Metal-2D Material-Metal (M-2DM-M) Configuration

In the proposed work, a novel architecture of a 10-channel hybrid time-wavelength division multiplexing/passive optical network (TWDM/PON) system is investigated for different data rates: low data rate (2.5 Gbps) and high data rate (10 Gbps) using different two-dimensional (2D) material-based photodetectors with a metal-2D material-metal (M-2DM-M) device structure. Integration with Silicon (Si)…

Flexural Behavior of Double-Layer Concrete Beams Composed of Normal and Steel Fiber-Reinforced Concrete

This investigation studies the flexural performance of double-layer reinforced concrete beams composed of ordinary concrete and steel fiber reinforced concrete (SFRC). The study evaluates the effects of bottom layer thickness, shear span ratio (a/d) and straight steel fiber volume fraction on structural behavior. The study project comprises twenty reinforced concrete beams, all specimens had…