Oncology News is Australia’s premier news service for Oncology professionals
Live Last read · last published · next check
Ultra-processed foods (UPFs) account for nearly 60% of adults’ and 70% of children’s energy intake in the United States. These industrially manufactured products – such as soft drinks, packaged cereals and snacks, and processed meats – are made with refined fats, oils, sugars, starches, salts and other additives that can enhance flavour, texture, and shelf [...]
A phase 3 trial found that five-fraction SBRT did not improve urinary quality of life or demonstrate superior disease-free survival compared with moderately hypofractionated IMRT in men with favourable intermediate-risk localised prostate cancer, although bowel-related quality of life favoured SBRT. For men with localised prostate cancer requiring radiotherapy, treatment is becoming increasingly…
An updated clinical guideline from the American Society for Radiation Oncology (ASTRO) provides evidence-based recommendations on the use of radiation therapy to treat adult patients with pancreatic cancer. The guideline updates ASTRO’s 2019 recommendations to reflect recent clinical trials that provide growing evidence for radiation therapy in the resectable, locally advanced and metastatic…
A research team has found that dyadic coping – the way couples jointly manage stress – partly explains the association between fear of cancer recurrence and depression among middle-aged and older survivors of gastrointestinal cancer. Survivors reporting greater fear tended to experience less effective coping with their spouses and more severe depressive symptoms. The findings [...]
Women receiving chest-wall radiotherapy after mastectomy reported more chest-wall symptoms five years later, while overall quality of life was otherwise similar between treatment groups. For women with intermediate-risk breast cancer, deciding whether radiotherapy is needed after mastectomy can involve a difficult balance between reducing recurrence risk and avoiding treatment-related harm. New…
A new study suggests a tissue-free ctDNA assay can detect molecular residual disease in early triple-negative breast cancer, with a similar median lead time to recurrence as a highly sensitive tumour-informed assay. For patients with early triple-negative breast cancer (TNBC), the end of treatment does not necessarily mean the end of uncertainty. Circulating tumour DNA [...]
Adding irinotecan to preoperative chemoradiotherapy failed to improve disease-free survival in patients with MRI-defined high-risk locally advanced rectal cancer — while substantially increasing treatment-related toxicity. For patients with high-risk locally advanced rectal cancer, intensifying preoperative treatment can seem attractive: if standard chemoradiotherapy helps control the tumour…
A large US cohort study found that the cumulative incidence of newly documented metabolic syndrome approached 40% during the first year after men started concurrent androgen deprivation therapy and an androgen receptor pathway inhibitor. Androgen deprivation therapy (ADT) is a cornerstone of treatment for advanced prostate cancer, but its effects extend beyond testosterone suppression. ADT [...]
A prospective multicentre study suggests that ultrasound-guided core needle biopsy can provide accurate tissue diagnoses with low complication rates in selected patients with pelvic tumours. For patients with a suspicious pelvic tumour, obtaining tissue is often essential to establish a diagnosis and guide treatment. But obtaining that tissue can sometimes mean a diagnostic laparoscopy or [...]
Cretostimogene produced complete responses in three-quarters of patients with high-risk, BCG-unresponsive non-muscle-invasive bladder cancer with carcinoma in situ in the phase 3 BOND-003 study. For patients with high-risk bladder cancer whose disease no longer responds to Bacillus Calmette-Guérin (BCG), the treatment choices can be stark. Once BCG-unresponsive disease persists or recurs, radical…