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Oncology News, Insights, Stories by OncoDaily · Aug 21, 2026

Chrystal Paulos: Can B Cells Make T Cell Therapy Stronger Against Solid Tumors?

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Eva Mkrtchyan · Oncodaily - Oncology News, Insights, Stories

Chrystal Paulos,Professor, Co-leader of the Cancer Immunology Program, and Director of Translational Research for Melanoma & Cutaneous Malignancies at Winship Cancer Institute of Emory University, shared by Winship Cancer Institute of Emory University on LinkedIn:

“Practical. Impactful. & a potentially easy way to bolster T cell therapy: add CpG! B cells aren’t just bystanders in the culture. They ‘coach’ CD8 T cells to become stronger cancer killers via a newly identified CD2 pathway, as shown by the brilliant Ayana Ruffin and our incredible collaborative team in Cancer Research!”

Quoting Winship Cancer Institute of Emory University:

“Researchers at Winship Cancer Institute of Emory University have discovered that B cells – immune cells best known for producing antibodies – can help train cancer – fighting T cells while those cells are being prepared for treatment.

The discovery may offer a practical way to make cell therapies more effective against solid tumors.”

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