To help raise awareness and openness regarding the effects of genetic mRNA vaccines on organs and tissue, NORTH Group is coordinating an outreach from concerned professionals to physicians working in General Pathology and subspecialities including:
Blood Banking/Transfusion Medicine
Bone & Soft Tissue Pathology
Breast Pathology
Cardiovascular Pathology
Cytopathology
Dermatopathology
Forensic Pathology
Gastrointestinal/Liver Pathology
Genitourinary Pathology
Gynaecologic Pathology
Head & Neck Pathology
Hematopathology
Molecular Pathology
Neuropathology
Paediatric Pathology
Pulmonary Pathology
Renal Pathology
Surgical Pathology
Medical professionals, including experienced pathologists, from several countries have contributed to the drafting of this letter. All agree that there has been a breach of medical ethics, a rejection of the precautionary principle and a lack of proper pharmacovigilance in the case of mRNA vaccines.
The letter has a short version and a long more comprehensive and science-based version. Link to the long version of the letter: https://northgroup.info/api/pdfs/patho-letter/20251103_Pathologists_letter_long_NORTH_Group.pdf
We believe that a respectful and understanding tone in communication is important for both the recipient and the sender of the letter.
• The letter is available in English on the NORTH Group website and will also be shared in other languages as it becomes available. Contact us if you would like a version in Word format.
• You can download the letter, adapt and translate it to your own language.
• You can send the letter to relevant professionals in your name, especially clinical pathologists or those working in forensic medicine or in the name of your organisation.
• If you send the letter in the name of NORTH Group and/or with the logo, the content must remain unchanged, except for translational adaptions.
• Please send any responses you receive to contactus@northgroup.info, or ask people to respond to this email address.
Dear Colleague,
We are writing to you as a fellow pathologist to solicit your professional expertise regarding histopathological observations that have been reported in the literature following the administration of modified mRNA COVID-19 vaccines.
As experts in histopathological diagnosis, we play a unique and critical role in identifying and understanding adverse event profiles for all medical interventions. Our duty of care extends beyond the individual case to contributing to the broader understanding of disease aetiology through meticulous observation and evidence-based analysis. A full evidenced based analysis of genetic vaccines is especially important given intentions to use this novel technology to replace traditional vaccines.
It is in this spirit of shared professional responsibility that we bring several peer reviewed publications to your attention. We are keen to learn whether your clinical experience aligns with, or diverges from, the findings described therein.
Request for Collaboration on Systematic Autopsy Findings:
Two recent systematic reviews have compiled global autopsy data from cases following COVID-19 vaccination, presenting findings we believe warrant discussion within our specialty:
1. Hulscher et al. (Jan 2024) [1]: This analysis of 28 deaths attributed to vaccine induced myocarditis found a mean time of 6.2 days from vaccination to death, with an average age of 44.4 years.2. Hulscher et al. (Nov 2024) [2]: A larger analysis of 325 autopsy cases found that 73.9% were independently assessed as directly caused or substantially contributed to by vaccination. The primary causes of death were cardiovascular (49% of cases), including sudden cardiac death (35%), myocardial infarction (12%), and myocarditis (7.1%).These studies propose, based on histological evidence and Bradford Hill criteria, a causal link. Their conclusion is that further systematic investigation is essential.
Observations from Histopathological Case Series:
The work of Prof. Arne Burkhardt and Dr. Ute Krüger, detailed in a recent histopathological atlas [3], reports prominent findings of:
Lymphocytic Vasculitis: Noted in nearly 90% of examined cases, involving inflammation of small and large vessels with associated endothelial damage.
Myocardial Inflammation: Observed in over 50% of cases.
Broader Context:
Beyond these core pathological studies, concerning signals have emerged at a population level, including patterns of non-COVID excess mortality [4,5,6,7,8], excess cardiac deaths [9, 10, 11], and changes in cancer presentation. Recent large-scale epidemiological studies are particularly noteworthy; a South Korean analysis of the national cohort found increased risks for hematological and other specific malignancies following vaccination [12], and a 30-month cohort study in an Italian province reported a significant increase in cancer hospitalization rates among the vaccinated population [13]. These population-level signals are consistent with the histological findings described above. A full list of references is provided below.
Our Core Questions for Your Professional Opinion:
Given these reports, we are keen to understand if your department has observed similar patterns over the past five years. Specifically:
1. Have you noted an increase in autopsies revealing unexplained lymphocytic myocarditis or systemic vasculitis, particularly in younger demographics?
2. In such cases, have you employed immunohistochemical staining (e.g., for spike and nucleocapsid proteins)? What were your findings?
3. Have you encountered cases of unusually aggressive or fast-presenting cancers that you have found notable from a diagnostic perspective?
4. Do you currently have access to, or would there be clinical interest in establishing, IHC protocols to better investigate these potential associations in relevant cases?
Our Shared Ethical and Legal Duty:
The principle of primum non nocere and our legal duty of care compel us to investigate such histological signals rigorously. When pathologists across multiple jurisdictions report consistent, unusual findings, it is our collective professional obligation to determine their significance. This is a question of diagnostic diligence and patient safety.
Collaborative investigation will either provide crucial reassurance by confirming the extreme rarity of these events or will lead to improved safety protocols, enhanced patient monitoring, and more informed consent.
Invitation to Share Your Experience:
We are advocating for enhanced professional awareness and formal, multi-centre study. Your firsthand experience is invaluable.
Have you seen similar histological changes? Do your observations differ?
We would be grateful for your confidential insights to help build a clearer picture.
Please share your comments with us at: contactus@northgroup.info
Thank you for your time and your consideration of this important professional matter.
With respect,
Dr. Clare Craig, BMBCh FRCPath, Diagnostic Pathologist, Chair HART Group
Dr. Ute Krüger, MD, Diagnostic Pathologist
For NORTHgroup.info
Dr. Jeanne Rungby, MD, Otorhinolaryngologist & Holistic medicine
Dr. Jonathan Gilthorpe, PhD, Associate Professor of Experimental Neuroscience
Dr. Sven Román, MD, Child and Adolescent Psychiatrist
Dr. Ros Jones, MD, FRCPCH, Retired Consultant Paediatrician
Hanna Parikka, MSc, Former IVF Biologist, Biotechnologist
Agita Galina, Mg.iur, BA, LlM, Lawyer & Social Worker
Dr. David J. Speicher, PhD, Molecular Virologist & Pathobiologist
KEY REFERENCES:
Autopsy & Histopathology:
1 Hulscher N, et al. (Jan 2024). Autopsy findings in cases of fatal COVID-19 vaccine-induced myocarditis. ESC Heart Failure. https://onlinelibrary.wiley.com/doi/full/10.1002/ehf2.146802 Hulscher N, et al. (Nov 2024). A Systematic Review of Autopsy Findings in Deaths After COVID-19 Vaccination. Public Health Policy Journal. https://publichealthpolicyjournal.com/asystematic-review-of-autopsy-findings-in-deaths-after-covid-19-vaccination/3 Krüger U, Lang W. (2025) Vaccinated - dead. A histopathological atlas. www.histo-atlas.comExcess Mortality:
4 Rancourt D, et al. (2024). Spatiotemporal variation of excess all-cause mortality in the world (125 countries) during the Covid period 2020-2023. Correlation-Canada.org. https://correlationcanada.org/covid-excess-mortality-125-countries/5 Sorli S. (2024). The Discrepancy Between the Number of Saved Lives with COVID-19 Vaccination and Statistics of Our World Data. https://www.longdom.org/open-access/thediscrepancy-between-the-number-of-saved-lives-with-covid19-vaccination-and-statistics-ofour-world-data.pdf6 Mostert S, et al. (2024). Excess mortality across countries in the Western World since the COVID-19 pandemic. BMJ Public Health. https://bmjpublichealth.bmj.com/content/2/1/e0002827 Alessandria M, et al. (2024). A Critical Analysis of All-Cause Deaths during COVID-19 Vaccination in an Italian Province. Microorganisms. https://www.mdpi.com/20762607/12/7/13438 Wrigley-Field E, et al. (2024). Mortality Trends Among Early Adults in the United States, 1999-2023. https://pubmed.ncbi.nlm.nih.gov/39888620/Cardiac Deaths:
9 British Heart Foundation. (2023). Excess deaths involving cardiovascular disease: an analysis. https://www.bhf.org.uk/what-we-do/policy-and-public-affairs/excess-deaths-involving-cardiovascular-disease-an-analysis - :~:text=Since the start of the,troubling situation in more detail10 Pulse Today. (2023). Heart disease continues to drive excess post-pandemic deaths, study finds. https://www.pulsetoday.co.uk/news/clinical-areas/cardiovascular/heart-disease-continuesto-drive-excess-post-pandemic-deaths-study-finds/11 Hulscher N, et al. (2024). Excess cardiopulmonary arrest and mortality after COVID-19 vaccination. https://www.opastpublishers.com/open-access-articles/excess-cardiopulmonaryarrest-and-mortality-after-covid19-vaccination-in-king-county-washington.pdfCancer Concerns:
12 Kim, H., Kim, MH., Choi, M. et al. 1-year risks of cancers associated with COVID-19 vaccination: a large population-based cohort study in South Korea. Biomark Res 13, 114 (2025). https://doi.org/10.1186/s40364-025-00831-w13 Martellucci A, et al. (2025). COVID-19 vaccination, all-cause mortality, and hospitalization for cancer: 30-month cohort study in an Italian province. https://doi.org/10.17179/excli20258400Further supporting references re excess mortality:
14. HART Group. (2023). We rightly mourn the dead but mustn’t forget the disabled. HART Group. (2023). A closer look at deaths in Australia in 2021 15. HART Group. (2023) Singapore: A case study. 16. HART Group. (2022) The impact of synthetic spike protein.17. Watson OJ, et al. (2022). Global impact of the first year of COVID-19 vaccination: a mathematical modelling study. Lancet Infect Dis. https://doi.org/10.1016/S14733099(23)00566-218. Ophir Y, et al. (2025). A Step-by-Step Evaluation of the Claim That COVID-19 Vaccines Saved Millions of Lives. https://www.fortunejournals.com/articles/a-stepbystep-evaluationof-the-claim-that-covid19-vaccines-saved-millions-of-lives.htmlFurther supporting references re cancer risk:
19. Senigl F, et al. (2024). The SV40 virus enhancer functions as a somatic hypermutation targeting element with potential tumorigenic activity. https://www.sciencedirect.com/science/article/pii/S266667902400017X20. NORTH Group. (Nov 2024). Letter of Concern to ministers of Health and Prime ministers. https://northgroup.info/pdfs/NORTH_Group_Letter-2024-11-25.pdf21. Dalby ER, Alegria C, UK PIP Analysis – Causes. https://phinancetechnologies.com/HumanityProjects/PIP%20Analysis-Causes.htmFor more info:
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