The Nigerian Journal of Basic and Clinical Sciences (ISSN: Print - 0331-8540) is a peer-reviewed journal published on behalf of the College of Health Sciences, Bayero University, Kano. The journal publishes high-quality and impactful research works, reviews, and proceedings relevant to health sciences. It also serves as a medium for publicizing meetings, conferences, the latest books, and news related to advances in health sciences in Africa and globally. The journal is published twice a year…
Introduction Breast milk is the optimal source of nutrition for newborns and is recommended exclusively for the first six months of life. Complementary feeding is introduced thereafter to meet a child’s nutritional needs, which is crucial for physical and neurocognitive growth during the first 1,000 days. This study assessed caregivers’ knowledge and practices regarding child nutrition and…
Introduction : Diabetes mellitus is a major global health burden that adversely affects male reproductive health through hyperglycaemia-induced oxidative stress, inflammation, hormonal disruption, and testicular damage, leading to impaired spermatogenesis and infertility. Conventional insulin therapy effectively controls glycaemia but offers limited protection against reproductive complications.…
Background: Northwest Nigeria is experiencing increasing temperatures due to climate change, posing significant health risks to its population, particularly outdoor workers and vulnerable groups like pregnant women and children. Objective: This study investigated the association between chronic heat exposure and physiological, cognitive, and maternal-child health outcomes in Northwest Nigeria.…
Background: Chronic Hepatitis B virus (HBV) infection is a major global health burden, particularly in Africa. Beyond hepatic disease, its association with neuropsychiatric conditions, especially depression, is increasingly recognised and may be mediated by inflammatory cytokines. Data from West Africa on this relationship are limited. Aim: This study investigated the association between serum…
Abstract Introduction: Diarrhea is a significant cause of morbidity and mortality among HIV-infected children, especially those with advanced disease. Although diarrhea among these children is caused by a multitude of factors, intestinal parasites are increasingly associated with decreasing levels of CD4+ cell count. This study aimed to determine the relationship between intestinal parasitic…
Molecular diagnostic capacity in low- and middle-income countries (LMICs) remains severely constrained by structural and logistical barriers, including inadequate cold-chain infrastructure, unreliable electrical supply, and shortages of trained laboratory personnel. Oxford Nanopore Technologies (ONT) sequencing platforms, particularly the MinION, offer a compelling alternative through physical…
Background: Prenatal exposure to heavy metals leads to cognitive deficits, preterm birth, low birth weight, lower IQ, and increased risk of respiratory disorders. Heavy metals impair neonatal health by causing oxidative stress, damaging developing organs, and disrupting neurodevelopment. Objectives: To determine the maternal and cord serum concentrations of toxic/heavy metals and its effect on…
Background: Postpartum depression (PPD) is a significant maternal mental health condition, particularly in low-resource settings where it is often underdiagnosed. Objective: To assess the prevalence, determinants, and coping mechanisms of PPD among postpartum women in Ogbomoso, Nigeria. Methods: A descriptive cross-sectional study was conducted among 120 women attending postnatal clinics at…
Background: Root canal treatment (RCT) is essential for maintaining functional dentition through debridement and obturation. This study assessed sociodemographic patterns, presentation trends, and pulpal status among patients at a tertiary hospital in South-West Nigeria. Methodology: A retrospective cross-sectional study reviewed clinical records of patients presenting for endodontic treatment at…
Female infertility represents a complex disorder with a significant but incompletely characterized genetic component. This case-control study investigates the hypothesis that polymorphisms in key one-carbon metabolism gene Methionine synthase reductase MTRR, contribute to infertility pathogenesis by inducing hyperhomocysteinemia and diminishing ovarian reserve. A cohort of 113 women from Calabar,…
