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Molly’s Substack · Jul 14, 2026

She Started the GLP-1 Microdosing Conversation. Here's What She's Saying Now

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Molly Sims · Molly’s Substack

She helped spark one of the biggest health conversations of the last few years—but according to Dr. Tyna Moore, the internet completely lost the plot. The naturopathic and chiropractic doctor, metabolic health expert, and host of The Dr. Tyna Show joins us to unpack what she originally meant by “microdosing” GLP-1 medications, why severe side effects may be a sign that a dose isn’t right for you, and how a nuanced conversation turned into a billion-dollar industry. Emese also shares her own experience taking Zepbound, leading to an honest discussion about whether GLP-1s are forever, who may benefit from them, and why lifestyle changes still matter. Plus, Dr. Tyna explains why your metabolism probably isn’t broken, the lab markers she looks at first, how chronic stress changes your body, and why strength training is non-negotiable for women as we age. If you’ve ever wondered whether GLP-1s are right for you—or felt confused by the endless noise online—this episode brings the conversation back to center.

“The snack food industry is hurting right now because of GLP-1s. Maybe all the other pharmaceuticals that people were on that they don’t need anymore when they’re on a GLP-1 — maybe there’s some vested interest there. Alcohol, people seem to want to not drink as much. They don’t want to smoke as much. There are a lot of big industries that profit off of us being slow, sick, dumb and fat. I hate to put it that frank, but they keep us there. And there are a lot of people who profit from that.”

“When interleukin-6 comes out of well-trained skeletal muscle that’s being squeezed, it’s anti-inflammatory. You can literally build an anti-inflammatory suit on your body. Think of muscle like a sink for all that excess blood sugar running around. You can’t build more of other organs in your body — but you can build more muscle. And no matter what age you are, you still can. There’s no end date on this. You’re never too old.”

“Stress makes you fat and it makes you ugly — I don’t know how else to say it. You start to gain weight that you can’t control, weight that isn’t responding the way you’re used to. That cortisol packs on right around the abdominal area. You get a gut. And then your face starts to change. You get thickened up and a lot of that’s cortisol. You can actually get cortisol resistance, just like insulin resistance. It’s not fine once you hit 50.”

Read the original on mollysims.substack.com

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