Mapping the Quaternary Landscape
Building a Machine Learning System for Protein Complex Prediction
bƒx(bioinformatics)
Latest posts
Burrows-Wheeler, Coronavirus, & Bayes
A Bioinformatics Pipeline to Detect & Understand COVID Mutants Fig 1. Molecular Structure with UK Mutant SARS-CoV-2 Docked to Human Receptor As the pandemic runs its course, tracking genetic mutations has gained mainstream coverage. Officially, in the line of work we call bioinformatics, finding and understanding mutations is known as Variant Calling. In the same way every person is different from…
Nucleotide analog to clog Viral RNA Polyermase machinery in nCoV-2019
Remdesivir is for sale as of today, at $3,120 USD for the treatment of our current pandemic. Gilead Sciences has been devolping this Nucleotide analog for over 10 years. Nucleotide analogs look like one of the letters that DNA & RNA are made up of (this one looks like the letter “A”). But it isn’t that letter, it just looks like it, it’s analogous to it. So molecular machines that interact with…
Using SARS-CoV-2 Reference Genome to Align Outbreak Sequencing Data
In this post we use the reference genome established by the CDC: Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome. To begin we need to grab just the FASTA data and save it as a file under something like nCoVref.fasta