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IV vs Inhaled Anesthetics: No Post-op Recovery Advantage

Propofol infusion may not offer better 30-day recovery or survival outcomes after major noncardiac surgery compared with inhaled anesthetics, a study finds. Medscape Medical News

Cefazolin Matches Penicillins for MSSA Bacteremia

A randomized trial finds cefazolin offers similar efficacy and less acute kidney injury than cloxacillin or flucloxacillin in adults with bacteremia. Medscape News Global

Can Deep Brain Stimulation Finally Deliver for Depression?

Nearly a decade ago, a landmark trial of deep brain stimulation for depression failed to show efficacy. Now researchers are trying again, and the stakes are higher than ever. Medscape Medical News

Adrenal Incidentalomas: Repeat Testing May Inform Management

About one1 in five5 patients with adrenal incidentalomas hadve changes in cortisol status over time, suggesting that routine repeat testing may influence management in selected patients. Medscape Medical News

Opioid Addiction May Up Complications After Hysterectomy

Opioid use disorder is associated with a higher risk for complications before discharge after inpatient removal of the uterus. Medscape Medical News

Symptoms May Signal Prostate Cancer in Primary Care

Patients presenting to primary care with prostate symptoms are more likely to be diagnosed with clinically significant prostate cancer than those without recorded symptoms. Medscape News UK

Newborns' Low Sodium Tied to Later Brain Disorders or Death

Hyponatraemia during the first 72 hours of life is linked to later neurodevelopmental disorders or death in infants with perinatal asphyxia. Medscape News UK

Migraine Tied to Earlier Stroke, Better Recovery

Migraine is linked to an earlier onset of stroke, yet young patients with stroke and a history of migraine experience better functional recovery at discharge. Medscape News UK

Ankle Strength Not Linked to Joint Hypermobility in Children

Ankle strength shows no clear association with foot posture or general joint hypermobility in children, with only weak links to lower limb hypermobility. Medscape Medical News

Poor Mental Health Tied to Risk for Drug Use Disorder

Poor mental health in US adults is linked to a significantly higher risk for a drug use disorder, with patterns often shaped by ADHD status, new research shows. Medscape Medical News

US Kindergarten Vaccine Coverage Continues Downward Trend, Falling 0.1%

U.S. kindergarten vaccination coverage fell 0.1% during the 2025-2026 school year, continuing a downward trend that has seen declines every year except one since the onset... Reuters Health Information

Doxycycline Cuts Recurrent Rectal Chlamydia Risk

A shift in prescribing practices at a Seattle sexual health clinic corresponded with a notable decline in recurrent rectal chlamydia cases among men who have sex with men. Medscape Medical News

Mild Tremor Tied to Cognitive Decline in Seniors

Even subtle hand tremor in older adults may signal more than just a benign motor quirk — new population data reveal an unexpected cognitive connection. Medscape Medical News

Cannabis Use May Increase Fall Risk in Adults With HIV

Among adults living with HIV, cannabis use is associated with an increased risk for falls — but the link weakens after accounting for other substance use and medications. Medscape Medical News

Explainer-How Congo's Ebola Outbreak Became the Second-most Lethal on Record

The ongoing Ebola outbreak is now the second-most lethal on record and the deadliest in the history of Democratic Republic of Congo. Only the epidemic in West Africa in... Reuters Health Information

Semaglutide and Depression: No Clear Link Found

A meta-analysis finds no significant association between use of semaglutide and risk for depression, although with limited certainty of evidence. Medscape Medical News

AstraZeneca Ditches Lung Cancer Treatment Trial

AstraZeneca has pulled the plug on a late-stage lung cancer trial for its drug Volrustomig. Press Association

VNS for RA a Year After Approval: Where Do Things Stand?

A year after approval of the first VNS device for rheumatoid arthritis, many patients are interested and providers in eight states are able to offer the device, but insurers are hesitating. Medscape Medical News

Obesity Class III Linked to Death Risk in Younger Adults

Younger adults with severe obesity face significantly increased risk for mortality, while older adults show minimal differences across obesity classes. Medscape Medical News

Integrase Inhibitors Safe for Heart in HIV Patients

A Swiss study tracking thousands of people with HIV found no long-term cardiovascular penalty when switching to integrase inhibitor-based therapy, though a small early-year uptick in events warrants clinical attention. Medscape Medical News

Gram-Negative Bacteria Lead Pediatric Cancer BSIs

Gram-negative bacteria account for nearly 70% of bloodstream infections in pediatric oncology patients, with nonsusceptibility rates of some organisms to antibiotics increasing. Medscape Medical News

Ca10H Linked to Improved Colorectal Cancer Outcomes

In a Spanish study of nearly 450 people, an atypical biomarker rose with adenomas and early disease — yet patients with higher levels had better long-term outcomes. Medscape News Europe

Early Dietitian Visits Linked to Successful Weight Loss

Routine primary care dietetic treatment achieves clinically relevant weight loss in one-third of adults with overweight or obesity, a Dutch study shows. Medscape Medical News

SLE Linked to Increased Risk for Venous Thromboembolism

Systemic lupus erythematosus is associated with an increased risk for venous thromboembolism, with the highest risk occurring in the first year after diagnosis. Medscape News UK

Diabetes Drug Curbs Weight Gain in Older People With HIV

Metformin, a common diabetes drug, curbs weight gain in older people with HIV over 96 weeks, but the effect reverses after treatment stops, a trial finds. Medscape News UK

Cigars, Pipes Up Lung Cancer Risk, Raise Screening Needs

Current or former use of cigars, cigarillos, or pipes increases the risk for lung cancer and may make more people eligible for low-dose CT screening, a study shows. Medscape News UK

Medical Therapy Reduces Nasal Discharge in CRS

Medical therapy significantly reduces nasal discharge symptoms in chronic rhinosinusitis, with benefits observed in both patients with nasal polyps and those without. Medscape Medical News

Pachychoroid Disease Progression Remains Low

Most eyes with pachychoroid features maintained their subtype over 2 years, with progression to pachychoroid neovasculopathy developing in only a small fraction of eyes. Medscape Medical News

Antioxidants in Vitiligo: Experts Support Select Ingredients

Experts say some antioxidants can improve vitiligo with or without phototherapy, but ingredients backed by evidence remain limited. Medscape Medical News

TIGIT Combo Fails to Improve Outcomes in Stage III NSCLC

Adding TIGIT blockade to PD-L1 inhibition failed to improve outcomes over durvalumab in patients with unresectable stage III NSCLC. Medscape Medical News