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Dramatic Increase in Active Surveillance Use for Prostate Cancer

(MedPage Today) -- Use of active surveillance for low- and favorable intermediate-risk prostate cancer more than tripled since 2005, according to a large study of veterans. In 2005 active surveillance accounted for 27% of men with low-risk prostate...

FDA Approves Activin Signaling Inhibitor for Bone Disorder

(MedPage Today) -- The FDA approved garetosmab (Pasatru) to reduce the formation of new heterotopic ossification lesions and disease flares in adults with fibrodysplasia ossificans progressiva (FOP), the agency announced on Wednesday. A monoclonal...

Robotic Phlebotomist Stand-In Gets FDA's Blessing

(MedPage Today) -- The FDA authorized the first robotic device that can independently draw patients' blood without a hands-on operator, the agency announced on Wednesday. The Aletta device uses near-infrared light and Doppler ultrasound to locate...

Here's How One Nephrology Unit Cut Hospital-Acquired C. Diff by 90%

(MedPage Today) -- An inpatient nephrology unit reduced hospital-acquired Clostridioides difficile (C. diff) infections by 90% after implementing nurse-driven protocols. Between January and April 2023, Detroit's Henry Ford Hospital nephrology...

Most Physical Activity Is Tied to Lower Dementia Risk, but This Type May Raise It

(MedPage Today) -- The relationship between physical activity and dementia risk may depend on whether the activity is recreational exercise or job-related labor, a study of more than 4.2 million people suggested. High physical activity levels...

Former Fauci Aide Pleads Guilty

(MedPage Today) -- David Morens, MD, a former top advisor at the National Institute of Allergy and Infectious Diseases (NIAID), pled guilty Tuesday in federal court to hiding government communications related to the COVID-19 pandemic. Morens...

Trump Picks Heidi Overton for FDA Commissioner: Here's What to Know

(MedPage Today) -- Heidi Overton, MD, PhD, a top White House aide, has been picked to lead the FDA, President Donald Trump announced Wednesday. Overton is the deputy director of the White House Domestic Policy Council who has worked on several...

No Nation Has Escaped Healthcare Rationing. Some Just Hide It Better.

(MedPage Today) -- The quest for a healthcare system devoid of rationing is, in economic terms, the pursuit of a mirage. While the moral imperative of medicine suggests that care should be a universal right provided without limit, the reality of...

Rise of Therapy Speak; Bipolar Treatment Review; White House Addiction Strategy

(MedPage Today) -- In a New York Times essay, a psychiatrist described how a growing number of teen girls and young women are using "therapy speak" to describe their mental distress, sometimes showing up at their first session announcing a diagnosis...

Nobel Prize Winner's 'Pedophile Operation'; Probe of EHR Giant; NIH K Award Changes

(MedPage Today) -- The New Yorker examined the sexual abuse of a famed NIH researcher who for decades brought dozens of young boys back to the U.S. from the Pacific islands. D. Carleton Gajdusek, MD, won the Nobel Prize in 1976 for his work on...

BMI Alone Questioned for Predicting Mortality Risk in Seniors

(MedPage Today) -- Central adiposity was linked to a higher mortality risk in older adults, independently of body mass index (BMI), according to longitudinal data from a survey study of Medicare beneficiaries. Over more than a decade of follow...

Citing Deaths, Docs Urge NCAA to Limit Energy Drink Marketing to Kids

(MedPage Today) -- A group of physicians and scientists are calling on the National Collegiate Athletic Association (NCAA) to make changes to its massive collaboration between Big 12 athletics and Monster Energy, citing potential health risks and...

Watchdog Urges HHS to Investigate Conflicts Among FDA's Peptide Panelists

(MedPage Today) -- A consumer watchdog group is demanding that the HHS Office of Inspector General (OIG) look into potential conflicts of interest among members of an FDA advisory committee that recommended that six peptides be added to the list...

The Doctors Who 'Don't See Pregnant Patients'

(MedPage Today) -- The resident was apologetic over the phone, embarrassed for reasons outside his control. He was transferring, from his hospital to ours, a pregnant patient who required consultation for a non-obstetric illness. This alone was...

SBRT Misses the Mark in Prostate Cancer Trial

(MedPage Today) -- Stereotactic body radiotherapy (SBRT) for localized prostate cancer did not improve urinary irritation or disease-free-survival (DFS) compared with hypofractionated intensity-modulated radiotherapy (IMRT), a large randomized...

Low-Dose Hydrocortisone Led to Cognitive Benefits in Women With HIV

(MedPage Today) -- Low-dose hydrocortisone (LDH) improved aspects of cognition in women with virally suppressed HIV, a randomized trial showed. In the first phase of the two-phase study, women who received a single 10-mg dose of oral LDH had significantly...

Autoinjectable PCSK9 Inhibitor; Caution on CoQ10; Ohio Doc's Rape Charges

(MedPage Today) -- The FDA approved the autoinjector version of lerodalcibep (Lerochol), a PCSK9 inhibitor for LDL cholesterol lowering, LIB Therapeutics announced. Bracco Imaging announced FDA clearance of its VueJect contrast delivery system...

GLP-1s and Birth Control; Retatrutide Lawsuits; Air Pollution and Menopause

(MedPage Today) -- Experts suggested that GLP-1 agonists may reduce the effectiveness of birth control pills. (The Hill) A phase III trial of avexitide, a first-in-class GLP-1 receptor antagonist, met its primary endpoint of reducing low blood...

Threat Monitoring, Legal Resources: How Hospitals Adapted to Abortion Bans

(MedPage Today) -- Hospitals in abortion ban states quickly developed standards to protect clinicians from legal risks when providing abortions in cases where the health or life of the mother is at risk, a qualitative study showed. Through interviews...

Study Finds Repeated NT-proBNP a Good General Health Test for Many Folks

(MedPage Today) -- A serially tracked heart stress (HS) biomarker was generally indicative of a person's heart risks in older age, even among relatively healthy individuals, an observational study showed. Based on the ASPREE trial and its extension...

School Vaccination Rates Inch Down and Exemptions Reach Record High

(MedPage Today) -- U.S. kindergarten vaccination rates inched down again last year and the share of children with exemptions rose to an all-time high, according to federal data posted Monday. The fraction of kids exempted from vaccine requirements...

Senators Blast RFK Jr. Over AHRQ Grant Cancellations

(MedPage Today) -- More than two dozen Democratic senators called on HHS Secretary Robert F. Kennedy Jr. to rescind recent grant cancellations by the Agency for Healthcare Research and Quality (AHRQ). "We write to express our profound concern...

Early Antivirals for Kids' Flu Linked to Lower Risk of Severe Outcomes

(MedPage Today) -- Early antiviral therapy at home for kids with influenza lowered the risk of related hospitalization, a retrospective case-control study from Taiwan indicated. Among 1,492 children, receiving antiviral therapy within 48 hours...

Vaccine Prevents Acute Gastroenteritis Deaths in Cases Caused by Rotavirus

(MedPage Today) -- Vaccination was highly effective at preventing death in children hospitalized with acute gastroenteritis caused by rotavirus infection, but its impact on mortality when rotavirus wasn't the culprit was less certain, according...

Congo's Fast-Moving Ebola Outbreak Becomes the Country's Worst

(MedPage Today) -- Congo's fast-moving Ebola outbreak has now killed over 2,300 people and become the deadliest outbreak of the disease on record in the Central African nation. The outbreak unfolding in one of Congo's most vulnerable regions is...

Multi-Joint Arthritis Bodes Poorly for Healthy Aging

(MedPage Today) -- Frailty worsened more for individuals with osteoarthritis (OA) affecting two or more joints versus those with single-joint or no OA, data from a long-running, population-based study indicated. Among more than 1,000 participants...

Scapegoating Fauci Won't Protect Us From the Next Pandemic

(MedPage Today) -- In my last column, I addressed why the Senate Homeland Security and Governmental Affairs Committee's decision to hold Anthony Fauci, MD, in contempt of Congress was legally flawed and procedurally unprecedented. But beyond the...

FDA-Approved Peanut Allergy Immunotherapy Exits Market

(MedPage Today) -- Not many allergists are mourning the exit of the first and only FDA-approved oral immunotherapy (OIT) product -- peanut allergy treatment Palforzia -- from the market. The standardized peanut protein product had been approved...

This Fetus Had a Parasitic Twin in an Unusual Location

(MedPage Today) -- An expectant mother learned her fetus had an extremely rare and life-threatening congenital anomaly, but a carefully executed procedure helped ensure a good outcome. After a local clinic identified a tumor around the face of...

Despite Vaccines, Most U.S. Adults Not Immune to Hepatitis A or B

(MedPage Today) -- Even with effective vaccines available, most U.S. adults don't have immunity to either the hepatitis A or B virus (HAV, HBV), according to a cross-sectional analysis, and recent federal vaccine recommendations could push immunity...

Nextstrain Aims to Boost Tracking of Virus Evolution

(MedPage Today) -- During the acute phase of the COVID pandemic, Nextstrain became known as a key platform for tracking the evolution of SARS-CoV-2. It took viral genome sequences uploaded to global repositories like GISAID and GenBank and turned...

Obesity Drugs Show Early Promise Against PMOS

(MedPage Today) -- Charlotte Touzalin was still a young teenager when she began struggling with weight gain, abnormal periods, and unwanted facial hair -- the same puzzling symptoms that plagued her mom for decades and that no doctor could piece...

Cold-Stored Platelets Safe in Cardiac Surgery

(MedPage Today) -- Extending the shelf life of platelets with refrigeration didn't hurt their hemostatic function for people undergoing complex cardiac surgery, the landmark CHIPS trial found. Platelets stored at 1-6°C (33.8-42.8°F...

Tommy John Dies; Fauci Called Again to Testify; Vasculitis Drug Pulled in Europe

(MedPage Today) -- Note that some links may require registration or subscription. Pitcher Tommy John, who won 288 games during his 26-year MLB career and became the first pitcher to successfully return following groundbreaking elbow surgery that...

'Same Disease, Very Different Access': What We Heard This Week

(MedPage Today) -- "Same disease, very different access." -- Fei Wang, PhD, of Breakthrough T1D in St. Leonards, Australia, discussing the state-by-state disparities in the U.S. in terms of type 1 diabetes incidence and access to pediatric endocrinologists...

Health AI Should be Assistive, Not Autonomous

(MedPage Today) -- A physician signs a progress note generated from an ambient recording. Another accepts a predictive risk score embedded in the electronic health record. A third submits an artificial intelligence (AI)-drafted appeal of an insurance...

Have Trouble Sleeping in a New Place? Most Do Because of the First-Night Effect

(MedPage Today) -- The first night in a new place is always the same for Robinson Leoni: He takes longer to fall asleep, wakes up more often during the night, and gets less sleep overall. At home he averages 7 hours. The first night away --...

New Polymyalgia Rheumatica Treatment; Genetic Treatment for Hypercholesterolemia

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of Texas Tech Health El Paso, look at the top medical...

Doctors Will Bear Witness to the Childhood Suffering

(MedPage Today) -- We are living in truly unprecedented times. On August 10, President Trump signed an executive order aimed at reshaping the nation's childhood immunization schedule, including directing HHS to pursue separate measles, mumps, and...

Before Killing Her Kids, Lindsay Clancy Searched About Hallucinations, Psychosis

(MedPage Today) -- Editor's Note: This story includes discussion of suicide. If you or someone you know needs help, the national suicide and crisis lifeline in the U.S. is available by calling or texting 988. Lindsay Clancy searched online about...

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