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Tiny Perfusion Letter · Aug 4, 2026

Tiny Perfusion Letter #827

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Luc Puis · Tiny Perfusion Letter

We can safely assume that cardiac surgery still is the discipline with the highest relative consumption of blood products

Many perfusionists are also responsible for cellsavers, acute normovolemic hemodilution, and hopefully member of a Patient Blood Management (PBM) Committee in the center where they work

Therefore, we’re focusing on some of the many resources available online on PBM, next to the more traditional literature sources

There is a TON of information out there on PBM, with many societies and possibilities for networking, listening to podcasts, attending conferences and email alerts

In random order:

  • Transfusion Evidence Library is an information resource…

  • Transfusion News brings you the latest news in blood banking…

  • AABB (Association for the Advancement of Blood & Biotherapies) is an international, not-for-profit association representing individuals and institutions involved… (they publish

  • Transfusion

  • IFPBM (International Foundation for Patient Blood Management) is a multi-faceted organization…

  • SABM (Society for the Advancement of Patient Blood Management) is an international, evidence-based educational resource network of excellence…

  • NATA (Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis - formerly known as Network for the Advancement of Transfusion Alternatives) is a global independent medical association…

  • Then there’s this guy — BloodBankGuy

Don’t say you didn’t know… 🙂‍↔️ 🩸🩸🩸

#enjoyandshare

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Central and Mixed Venous Oxygen Saturation in Cardiac Surgery: A Systematic Review and Meta-Analysis

Guarnieri M, Baggio L, Amendolagine L, Mincolelli A, De Cari D et al.

J Cardiothorac Vasc Anesth. 2026 Jul 5. Online ahead of print OPEN ACCESS

Understanding Pressure Excursions in Extracorporeal Technologies: The Role of Shear Stress and Hematologic Predisposition.

El Dsouki Y, Cirullo C, D’Alessandro A, Condello I.

J Extra Corpor Technol. 2026 Jun;58(2):205-207 OPEN ACCESS

Estimation of Hemoglobin Concentration at the Initiation of Cardiopulmonary Bypass Using Support Vector Regression.

Hirano H, Takahashi S, Kamei T, Hibiya M.

J Extra Corpor Technol. 2026 Jun;58(2):128-138 OPEN ACCESS

Comparison of Clinical Outcomes between Pulsatile and Non-pulsatile Perfusion during Cardiopulmonary Bypass: A Prospective Randomized Study.

Sharma A, Luitel P, Khakural P, Sapkota R.

J Extra Corpor Technol. 2026 Jun;58(2):117-123 OPEN ACCESS

Simulation Use in Perfusion Education: A 2025 Survey of United States Programs.

Bienstock J, Searles B, Darling E.

J Extra Corpor Technol. 2026 Jun;58(2):102-109 OPEN ACCESS

Integration of the Korean and World Databases for Pediatric and Congenital Heart Surgery: A Model for Global Registry Collaboration.

St Louis JD, Bateson BP, Broser T, Jeong CL, Rudraraju R et al.

World J Pediatr Congenit Heart Surg. 2026 Jun 30. Online ahead of print

Field-effect Transistors for Electrophysiological Monitoring of Cardiac and Nervous System.

Zhang T, Li H, Li N, Zhao X, Meng Q et al.

Biosens Bioelectron. 2026 Nov 1;311:118917

A Heart-on-a-chip Simultaneously Monitoring Contractility and Troponin Secretion Under Dynamic Mechanical Stimulation

Zhang W, Wang Y, Yu J, Wang K, Xing L et al.

Biosens Bioelectron. 2026 Nov 1;311:119002

Head–core Temperature Discordance during Hypothermic Circulatory Arrest in Acute Type A Aortic Dissection

Wakisaka H, Takashima N, Suzuki T.

JCTVS Open. 2026 Jul 1. Online ahead of print OPEN ACCESS

Cerebral Autoregulation During Antegrade Cerebral Perfusion in Neonates Undergoing Congenital Cardiac Surgery

Fang ZA, Marino BS, Brady KM.

J Cardiothorac Vasc Anesth. 2026 Jul 10. Online ahead of print

Fluid Balance during PICU Stay in Children after Cardiac Surgery with Cardiopulmonary Bypass.

Luppes VAC, Pamir Z, Blom NA, Hazekamp MG, Roeleveld PP et al.

Eur J Pediatr. 2026 Jul 10;185(8):566 OPEN ACCESS

Feasibility and Safety of a Novel Activated Leukocyte Adsorption Device during Cardiopulmonary Bypass: A First-in-human Pilot Study.

Yan W, Zhang W, Mao X, Yuan H, Xiong Y.

Sci Rep. 2026 Jul 7. Online ahead of print OPEN ACCESS

Sex-Related Long-Term Outcomes in On-Pump Coronary Artery Bypass Grafting-A Propensity Score-Matched Analysis.

Knochenhauer T, Sobik F, Pausch J, Detlef I, Brickwedel J et al.

Interdiscip Cardiovasc Thorac Surg. 2026 Jul 1;41(7):ivag186 OPEN ACCESS

The Association of Estimated Citrate Load with Frozen Plasma versus Four-factor Prothrombin Complex Concentrate for Coagulopathy after Cardiac Surgery: A Post Hoc Exploratory Analysis of the FARES-II Randomised Controlled Trial.

Tanaka KA, Butt AL, Stewart KE, Pezeshki G, Werner S et al.

BJA Open. 2026 Jun 29;19:100577 OPEN ACCESS

Effect of the Duration of Cardiopulmonary Bypass on Oxygenation Predicted by Measuring Thoracic Fluid Content Using Electrical Cardiometry in Infants Undergoing Closure of Ventricular Septal Defect:A Prospective Observational Study.

Laguduva AH, Gharde P, Chauhan S, Ramakrishnan L, Prakash M et al.

J Cardiothorac Vasc Anesth. 2026 Jun 11. Online ahead of print

The MAMBO Framework and the Future of Modern Perfusion: Artificial Intelligence, Cognitive Ergonomics, and Sustainable Workflow Integration.

Condello I, El Dsouki Y.

Cureus. 2026 Jun 8;18(6):e110501 OPEN ACCESS

Silent Cerebral Infarction after Proximal Thoracic Aortic Surgery under Deep Hypothermic Circulatory Arrest: An Exploratory Prospective DW-MRI Study.

Bozkurt B, Akıncı O, Kuş MK, Ören C, Yıldız Z et al.

BMC Cardiovasc Disord. 2026 Jul 6. Online ahead of print OPEN ACCESS

Conceptions of Human Factors in Simulation-based Education: A Phenomenographic Study.

Kitt A, Kainth R.

Adv Simul (Lond). 2026 Jul 8.Online ahead of print OPEN ACCESS

Partial Carina Resection, Reconstruction, and Left Pneumonectomy under Median Sternotomy Combined with Cardiopulmonary Bypass: A Case Report.

Guo Y, Wang J, Zhang G, Tong T, Jin C.

J Cardiothorac Surg. 2026 Jul 19.Online ahead of print OPEN ACCESS

Partial Cardiopulmonary Bypass in Thoracoabdominal Aorta Repair: A Safe Alternative in a Low-volume Center.

Nunez-Ordonez N, Senosiain J, Sarmiento JA, Villa CA, Obando C et al.

J Cardiothorac Surg. 2026 Jul 19. Online ahead of print OPEN ACCESS

Predictive Value of Preoperative Hematologic Inflammation Indices (NLR, PLR, SII) and Clinical Risk Factors in Predicting Postoperative Pulmonary Complications after Elective Isolated On-pump Coronary Artery Bypass Grafting: A Retrospective Cohort Study of 1034 Patients.

Vezir Ö, Tekin EE.

J Cardiothorac Surg. 2026 Jul 18. Online ahead of print OPEN ACCESS

Efficacy and Safety of Prothrombin Complex Concentrate versus Fresh Frozen Plasma in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis.

Hameed MS, Razzaq A, Zia A, Iftihar A, Zaeem M et al.

J Cardiothorac Surg. 2026 Jul 17. Online ahead of print OPEN ACCESS

Mortality-related Predictors in Patients Receiving Extracorporeal Membrane Oxygenation after Coronary Artery Bypass Grafting: A Retrospective Study.

Zhang C, Feng C, Zhang P, Kan Y, Liu A et al.

J Cardiothorac Surg. 2026 Jul 5. Online ahead of print OPEN ACCESS

Risk Factors and Outcomes of Early Postoperative Complications Following Congenital Heart Surgery: A Retrospective Study at a Tertiary Care Hospital in Nairobi, Kenya.

Adan NI, Orwa J, Ahmed I, Awori M, Del Rossi S.

J Cardiothorac Surg. 2026 Jul 25. Online ahead of print OPEN ACCESS

Imbalance between Oxygen Delivery and Consumption during Cooling and Rewarming Phases of Cardiopulmonary Bypass and Association with Hyperlactatemia in Total Aortic Arch Replacement: A Prospective Observational Study.

Peng L, Wei W, Du L, Xiong J.

J Cardiothorac Surg. 2026 Jul 20. Online ahead of print OPEN ACCESS

Direct Axillary Artery Cannulation With the Open Seldinger Technique.

Karaağaç A, Gökçe I, Arslanhan G, Bastopcu M, Ozcan ZS et al.

CTSNET. 2026 Jul 9. OPEN ACCESS

Pericardial Fluid Cardiac Troponin I Predicts Postoperative Atrial Fibrillation after Coronary Artery Bypass Grafting.

Shu Y, Gao C, Ren X, Deng X, Luo L. et al.

JCTVS Open. 2026 Jul 6. Online ahead of print OPEN ACCESS

Determinants of Postoperative Recovery after Cardiac Surgery in Older Adults: A Multidimensional Cross-sectional Study.

Basli A, Işıklı A, Hüseyin S.

Heart Lung. 2026 Jul 25;80:102893. Online ahead of print

Coagulation-Friendly Environment in Cardiac Surgery. A Narrative Review.

Yévenes F, Bolliger D, Di Dedda U, Ahmed A, Koller T et al.

J Cardiothorac Vasc Anesth. 2026 Jul 12. Online ahead of print

Distinct Goal-directed Perfusion Signatures in Donation after Brain Death versus Circulatory Death Heart Transplantation.

Wang C, Ahmad A, Petrovic M,

JHLT Open. 2026 Nov:14;100630. Online ahead of print OPEN ACCESS

Proteomic, Transcriptomic, and Metabolic Mediators of Post-Cardiopulmonary Bypass Vasoplegia Syndrome.

Galloway A, Magro C, Goparaju C, Phillips K, Tokoro K et al.

J Thorac Cardiovasc Surg. 2026 Jul 15. Online ahead of print

Evaluation of Activated Clotting Time Response to Unfractionated Heparin in Vascular Surgery: An Observational Study.

Garberi R, Milan M, Palermo R, Segramora VM, Casati M et al.

J Cardiothorac Vasc Anesth. 2026 Aug;40(8):2466-2473 OPEN ACCESS

Preoperative Glycocalyx Status and Postoperative Organ Failure after Cardiac Surgery in the GLYPOCS Observational Cohort Study.

Molkhou C, Demailly Z, Ait-Ali C, Kouadri G, Clavier T et al.

J Cardiothorac Vasc Anesth. 2026 Jul 21. Online ahead of print OPEN ACCESS

Blood Glucose Variability and Postoperative Organ Function in Coronary Artery Bypass Grafting: A Prospective Cohort Study of Microcirculatory Perfusion and Oxygenation.

Mansjoer A, Alwi I, Yunir E, Aditianingsih D, Harimurti K et al.

J Cardiothorac Vasc Anesth. 2026 Jul 29. Online ahead of print OPEN ACCESS

Pulses That Predict: Postoperative Perfusion Index and Outcomes in High-risk Pediatric Cardiac Surgery.

Cater DT, Friedman ML, Murphy LD, Puranik P, Turrentine MW, Lutfi R.

J Thorac Cardiovasc Surg. 2026 Aug;172(2):271-279

Artificial Intelligence for Predicting Perioperative Outcomes in Cardiac Surgery: A Systematic Review.

Ha J, Vohra HA.

Innovations (Phila). 2026 Jul 13. Online ahead of print OPEN ACCESS

Promoting Psychological Safety for All Participants During a High-Intensity Interprofessional Simulation Event.

Greene EA, Williams JK, Nicholson RM, Kumer KD, Best NI et al.

Simul Healthc. 2026 Aug 1;21(4):247-251

Laboratory Monitoring Unfractionated Heparin Treatments: Unanswered Issues.

Toulon P.

Int J Lab Hematol. 2026 Jul 14. Online ahead of print

Heparin Dose-Response Curve for Heparin Dose Determination During Cardiopulmonary Bypass for Pediatric Cardiac Surgery: A Prospective Randomized Controlled Study.

Gokhale P, Hasija S, Choudhury A, B SG, Yadav M, Chauhan S.

J Cardiothorac Vasc Anesth. 2026 Jun 27. Online ahead of print

Concordance of Activated Partial Thromboplastin Time and Anti‒Factor Xa Levels in Monitoring Heparin Therapy Among Cardiac Surgery Patients in Pre- and Postoperative Settings.

O’Connor K, Cassiere HA, Islam S, Chang TY, Sherman N, Yu PJ.

J Cardiothorac Vasc Anesth. 2026 Jun 23. Online ahead of print OPEN ACCESS

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Adequate Venous Drainage Does Not Exclude Cannula Malposition: Right Ventricular Perforation during Minimally Invasive Aortic Valve Replacement.

Oue K, Kinoshita M, Okuda S, Kondo N.

Surg Case Rep. 2026;12(1):26-0380 OPEN ACCESS

Harbinger of Difficult Weaning from Cardiopulmonary Bypass in Aortic Valve Replacement Surgery: A Case Report.

Deepak A, Kuppuswamy B, Davis K, Andugala SS.

Ann Card Anaesth. 2026 Jul 1;29(3):430-433 OPEN ACCESS

Relationship Between Entropy-Guided Sevoflurane Administration and End Oxygenator Sevoflurane Concentration in Adult Patients Undergoing Cardiopulmonary Bypass Surgery.

Kumar V, Kumar A, Gourav KP, Devarakonda B.

Ann Card Anaesth. 2026 Jul 1;29(3):378-385 OPEN ACCESS

Combining Biomarkers with Clinical Risk Factors to Predict Acute Kidney Injury after Cardiopulmonary Bypass Surgery: An Observational Cohort Study.

Xu X, Liang Y, Shi S, Si H, Cheng A et al.

Medicine (Baltimore). 2026 Jul 10;105(28):e49765 OPEN ACCESS

Superiority of Fibrinogen Concentrate Versus Cryoprecipitate for Treatment of Bleeding in Cardiac Surgery Patients: A Secondary Analysis of the FIBRES Randomized Clinical Trial Stratified by Surgical Risk.

Bartoszko J, Karkouti K, Callum JL.

J Cardiothorac Vasc Anesth. 2026 Jun 17. Online ahead of print OPEN ACCESS

Clinical Effectiveness of Acute Normovolemic Hemodilution in Cardiac Surgery: A Systematic Review and Meta-analysis.

Elfiki M, Elfeky A, Ali MS, Ibrahim A, Zayed M et al.

Anesth Analg. 2026 Jul 13. Online ahead of print

Is Preoperative Serum Bicarbonate an Undervalued Risk Factor in Cardiac Surgery?

Chorney W, Hinchion J.

J Cardiovasc Transl Res. 2026 Jul 13;19(1):89 OPEN ACCESS

Postoperative Hematocrit and Lactate Trajectory After Neonatal Cardiopulmonary Bypass: A Retrospective Cohort Study.

Rehman MU, Whitehorn M, Torgerson D, Fineman JR, Steurer MA.

Pediatr Cardiol. 2026 Jul 24. Online ahead of print OPEN ACCESS

Association Between Preoperative Hydration and Cardiac Surgery-associated Acute Kidney Injury: A Prospective Observational Study.

Mohsen G, Wallqvist J, Lee ZY, Buckenmayer A, Oppenkowski JV et al.

J Cardiothorac Surg. 2026 Jul 23;21(1):505 OPEN ACCESS

Sevoflurane Diffusion Across Four Paediatric Cardiopulmonary Bypass Oxygenators: A Laboratory Investigation.

Dubernet M, Bonnet V, Vanden Dorpe T, Hennart B, Wiart JF, Moussa MD.

Br J Anaesth. 2026 Jul 2. Online ahead of print

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