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Lucas Harrington

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Wealthy Individuals Funding Science is Good for Everyone

Private wealth funded most of history's scientific breakthroughs. Stigmatizing it now is holding us all back.

The Practical Guide to Biotech Partnerships

From First Date to Long-term Commitment: Lessons Learned from $200M of upfronts at Mammoth In biotech, a single strategic partnership can transform a company s trajectory for better or worse. As equity financings become increasingly challenging, this is more true than ever. However, while headlines trumpet billion-dollar deal values, the reality is that partnerships should [ ]

The CRISPR Baby Ban Isn’t Working. What We Should Do Instead

Development of germline editing continues in the shadows. It s time to replace prohibition with responsible regulation. The idea of changing a baby s DNA before birth stands as one of modern science s most controversial frontiers framed by futurists as humanity s next evolutionary step and by opponents as modern eugenics. The time has come to break [ ]

AI for Biology Could Eclipse LLMs: Thoughts on What Stands in the Way

The impact of AI for Biology could be enormous but there are unique challenges to biological data that will require distinct breakthroughs instead of copy and pasting success with LLMs Current state of AI for Biology If successful the opportunity for bio AI is enormous. I would argue the impact could be larger than the [ ]

Overcoming CRISPR’s Biggest Hurdle: Genetic Disease Diversity

The actual biggest challenge for CRISPR that seldom gets talked about When CRISPR emerged in 2012, the headlines promised a cure for all genetic diseases. Yet today, despite being one of the most rapidly developed new therapeutic modalities, CRISPR is only used to treat a few dozen of the 7000+ known genetic diseases. Why? Ask [ ]