A new study suggests that in amyotrophic lateral sclerosis – and possibly other neurodegenerative diseases – the brain’s immune cells devour stressed but still living neurons due to altered signaling [1]. The living dead Amyotrophic lateral sclerosis (ALS), […]
Using cohort studies and a mouse model, researchers have found that the circulating factor ANGPTL8, which is produced by senescent fat cells, is related to age-related diseases and mortality in mice and people. Too […]
This AI startup, which lists Nobel laureate David Baker among its co-founders, has announced a “world model” of a cell that can simulate both its natural […]
Researchers have gone into deep detail regarding how each of five senescent brain cell types expresses and receives factors that encourage other cells to become senescent. […]
A massive human genetics study identified rare folliculin-interacting protein 1 (FNIP1) mutations associated with favorable metabolism and much lower cardiometabolic disease risk. Experiments in human liver cells and mice suggest a therapeutic route [1]. Longevity […]
In Aging, the Conboys and their team have described how a combination treatment kills both senescent and cancer cells and lengthens the lives of old mice. Of senescence and cancer Just […]
Staying informed about health and longevity interventions can be tedious and time-consuming. Often it involves manually decoding a supplement label with numerous compounds, reading a blog post about some therapy, or an X-post that name-drops a peptide […]
A recent study identified the thymus hormone thymulin as a molecule with the potential to reduce inflammation in an age-dependent manner. Treating cancer-bearing mice with this molecule made other cancer treatments more effective [1]. The aging immune system Aging […]
A new study proposes a theoretical framework that explains why the more complex an animal is, the harder it is to move the needle on its rate of aging [1]. A problem of great […]
Researchers have discovered why the protein AGGF1 has significant effects on blood pressure and published their findings in Aging Cell. Blood pressure is a condition of its own The authors begin their paper by discussing […]