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Living in an Ivory Basement

Stochastic thoughts on science, testing, and programming.

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Announcing taxburst, an update of the Krona software for taxonomy exploration

Announcing taxburst for metagenome taxonomy!

Announcing: the chill-filter Web site - DNA sample composition at a glance!

what's in my sample, dude?

Why Rust is an increasingly beloved part of my programming toolbox

Rust is nice!

Recent advances in the sourmash ecosystem (August 2024)

sourmash is faster and better than before!

Speeding sourmash the heck up

Faster things are always nice, right?

The history of the "Tragedy of the Commons"

No, just no.

Sourmash and branchwater licensing: thoughts on extractive engagement with projects

What licenses should be used, for what purpose?

snakemake for doing bioinformatics - inputs and outputs and more!

Slithering your way into bioinformatics with snakemake - inputs and outputs and more!

snakemake for doing bioinformatics - using wildcards to generalize your rules

Slithering your way into bioinformatics with snakemake, wildcard version

conda & mamba on shared clusters works better now!

conda is great!

A brief overview of automation and parallelization options in UNIX/on an HPC

Automating things! Parallelizing them!

snakemake for doing bioinformatics - a beginner's guide (part 2)

Slithering your way into bioinformatics with snakemake, round 2.

snakemake for doing bioinformatics - a beginner's guide (part 1)

Slithering your way into bioinformatics with snakemake

sourmash has a plugin interface!

Enabling plugins in sourmash, for less directed & more incoherent progress!

Reading "Orwell's Roses" by Rebecca Solnit

This is a good book!

So! You want to search all the public metagenomes with a genome sequence!

Searching all the things - faster!

Announcing ribbity - a hacky project to build Web sites from GitHub issue trackers

Munging GitHub issue trackers for fun!

The second Common Fund Data Ecosystem hackathon - May 9-13, 2022!

We're running another hackathon!

Storing 64-bit unsigned integers in SQLite databases, for fun and profit

Storing unsigned longs in SQLite is possible, and can be fast.

The First Common Fund Data Ecosystem Hackathon

We ran a successful pilot hackathon, and we will run a second one soon!

On minimum metagenome covers, and calculating them for your own data.

You, too, can run our software!

A bioinformatics training career panel in the DIB Lab

Careers in training!

Using snakemake to do simple wildcard operations on many, many, many files

snakemake is awesome

A biotech career panel in the DIB Lab

Careers outside of universities!

Scaling sourmash to millions of samples

Bigger and better!

New sourmash databases are available!

Databases are now available for GTDB!

Moving sourmash towards more community engagement - a funding application

CZI EOSS4 application for sourmash support

Searching all public metagenomes with sourmash

Searching all the things!

sourmash 4.1.0 released!!

sourmash v4.1.0 is here!

sourmash 4.0 is now available! Low low cost if you buy now!

sourmash v4.0.0 is here!

sourmash v4.0.0 release candidate 1 is now available for comment!

sourmash v4.0.0 is coming!

Transition your Python project to use pyproject.toml and setup.cfg! (An example.)

Updating old Python packages, in this year of the PSF 2021!

A snakemake hack for checkpoints

snakemake checkpoints r awesome

Improved workflows-as-applications: tips and tricks for building applications on top of snakemake

Writing applications around workflow systems, take 2.

sourmash databases as zip files, in sourmash v3.3.0

Use compressed databases directly!

Software and workflow development practices (April 2020 update)

How we develop software and workflows in the DIB Lab, in 2020.

How to give a bad online talk

A bad example...

Some snakemake hacks for dealing with large collections of files

snakemake4life

Two talks at JGI in May: sourmash, spacegraphcats, and disease associations in the human microbiome.

Using k-mers and taxonomy to find contamination in metagenomes

sourmash-oddify: a workflow for exploring contamination in metagenome-assembled genomes

Using k-mers and taxonomy to find contamination in metagenomes

Finding problematic bacterial/archaeal genomes using k-mers and taxonomy

Some things in Genbank look ...odd.

How does sourmash's lca classification routine compare with GTDB classifications?

GTDB databases again!

Sourmash LCA databases now available for the GTDB taxonomy

GTDB databases!

An initial report on the Common Fund Data Ecosystem

Helping DCCs get FAIRer

Comparing two genome binnings quickly with sourmash

Comparing two sets of MAGs, for fun and profit!

How to encourage participation in teleconferences

Participation is good!

Using GitHub for janky project reporting - some code

We scripted GitHub for lightweight project reporting

Some questions and thoughts on journal peer review.

What's up with current peer review practice?

Things to think about when developing shotgun metagenome classifiers

Thoughts on goals and tradeoffs in classifying shotgun metagenome data.

Our submission for the NHGRI Human Genome Reference Center call

We wrote a big grant proposal!