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Climate change is increasingly recognized as a critical determinant of health system performance, disrupting healthcare delivery through extreme weather events, infrastructure instability, and evolving disease patterns. Despite growing awareness, the operational integration of climate resilience into routine health system governance remains limited. We propose the Climate-Adaptive Clinical…
Background: Postmenopausal women and people with rheumatoid arthritis face accelerated bone loss and higher fracture risk through overlapping mechanisms including estrogen deficiency and chronic inflammation. Given limitations and adverse effects of long‑term pharmacotherapy, effective non‑pharmacological strategies are needed. This review summarizes recent evidence on lifestyle, exercise,…
Health system resilience increasingly depends on digital architectures that support continuity of care, adaptive decision-making, and sustained performance during crises. Despite the rapid expansion of digital data collection, fragmentation and limited interoperability continue to constrain its utility. Resilient digital health systems require interoperable standards, embedded clinical decision…
Background: The COVID-19 pandemic disrupted maternity care and amplified psychological distress among pregnant women. Those diagnosed with COVID-19 faced intensified worries about their own health, fetal wellbeing, and loss of support. This study aimed to explore the lived experience of fear of maternal and fetal loss in pregnant women with COVID-19. Materials and Methods: This qualitative…
Background: Artificial intelligence (AI) is a cornerstone of digital health with transformative potential in diagnosis, medical imaging, and clinical management. Clinical translation is constrained by data quality, interpretability issues, and ethical‑legal gaps. This study maps the global AI landscape and evaluates opportunities, barriers, and the infrastructural readiness of Iran's healthcare…
Background: Infertility is associated with substantial psychological and spiritual distress. In pronatalist societies, women with primary infertility-even when attributed to male-factor causes-often experience disproportionate stigma and emotional burden. Spiritual well-being (SWB) may serve as an important coping resource. This study aimed to assess SWB and its socio-demographic, clinical, and…
Antimicrobial resistance (AMR) is widely recognized as one of the most pressing public health challenges of our time, compromising the effectiveness of standard treatments and imposing substantial human and economic costs. If not addressed proactively, AMR may gradually weaken health systems' ability to control infections and sustain the achievements of modern medicine. In countries such as…
Background: Isoflavones are soy-derived phytoestrogens that may influence bone remodeling differently according to age, sex, hormonal status, dosage, and metabolism. This study evaluated their effects on bone mineral density (BMD), bone mineral content (BMC), and bone turnover markers in children, adolescents, and adults to clarify their potential role in bone health and osteoporosis…
Background: Cardiac disease substantially impairs quality of life (QoL). Although psychosocial factors influence health outcomes, the mechanisms through which health literacy (HL) affects QoL in patients with cardiac disease remain unclear. This study examined the association between HL and QoL, with social support (SS) as a mediator and spiritual well-being (SWB) as a moderator. Materials and…