The Glutamine-Glutamate cycle and Chronic Disease

Quick-hitting no-brainer here (as most of them are, actually).

1. The Glutamine-Glutamate Cycle is involved in lots of chronic diseases, especially involving the brain.

2. Our foods are LOADED with Manufactured free Glutamates (MfG’s) that overload our bodies with free Glutamates, which in turn affects our Glutamine-Glutamate Cycle.

What could go wrong?

Below is the AI Overview of a search for “glutamine glutamate cycle chronic disease”, and below that a list of commonly found MfG’s in our foods.

You honestly don’t need a medical degree to figure this out, but “Look…a squirrel!”

That’s how health is done today.

“The glutamine-glutamate cycle is a process that regulates the levels of glutamate and glutamine in the body, which is important for preventing chronic diseases:

• Glutamate excitotoxicity

  The cycle prevents glutamate excitotoxicity, which can occur when glutamate receptors are overstimulated or chronically stimulated. This can lead to cell damage and inflammation.

• Neural communication

  The cycle helps regulate the production of glutamate-derived neurotransmitters, which are important for neural activity.

• Mitochondrial dysfunction

  Dysregulation of glutamine levels can lead to mitochondrial dysfunction, which can ultimately cause cell death.

• Neurological diseases

  Defects in the glutamine-glutamate cycle can lead to neurological diseases such as Alzheimer's disease, Parkinson's disease, schizophrenia, and depression.

• Hepatic encephalopathy

  Hyperammonemia and hepatic failure can alter glutamatergic neurotransmission, which can lead to hepatic encephalopathy (HE). HE can cause damage to learning and memory.

• Mental health disorders

  Problems with making or using glutamate have been linked to mental health disorders such as autism, depression, and schizophrenia.

• Neurodegenerative diseases

  Too much glutamate exciting nerve cells has been associated with neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease.” SOURCE

Glutamic acid (E 620)
Glutamate (E 620)
Monosodium glutamate (E 621)
Monopotassium glutamate (E 622)
Calcium glutamate (E 623)
Monoammonium glutamate (E 624)
Magnesium glutamate (E 625)
Natrium glutamate
anything “Hydrolyzed”
any “Hydrolyzed protein”
Calcium caseinate, Sodium caseinate
Yeast extract, Torula yeast
Yeast food, Yeast nutrient, Nutritional yeast
Autolyzed yeast, Brewer's yeast
Gelatin
Textured protein
Whey protein
Whey protein concentrate
Whey protein isolate
Soy protein
Soy protein concentrate
Soy protein isolate
anything “Protein”
anything “Protein fortified”
anything "Protein concentrate"
anything "Protein isolate"
Zinc proteninate
anything "Proteninate"
Soy sauce
Soy sauce extract
Protease
anything “Enzyme modified”
anything containing “Enzymes”
anything “Fermented”
Vetsin
Ajinomoto

Carrageenan (E 407)
Bouillon and broth
Stock
any “Flavors” or “flavoring”
Natural flavor
Maltodextrin
Oligodextrin
Citric acid, Citrate (E 330)
anything “Ultra-pasteurized”
Barley malt
Malted barley
Pectin (E 440)
Malt extract
Seasonings
Soy milk

Corn starch
Corn syrup
Modified food starch
Lipolyzed butter fat
Dextrose
Rice syrup
Brown rice syrup
Milk powder
Reduced fat milk (skim; 1%; 2%)
most things “Low fat” or “No fat”
anything “Enriched”
anything “Vitamin enriched”
anything “Pasteurized”
Annatto
Vinegar
Balsamic vinegar
certain Amino Acid Chelates (Citrate, Aspartate, and Glutamate are used as chelating agents with mineral supplements.)

Disodium 5’-guanylate (E 627) / Disodium 5’-inosinate (E-631) / Disodium 5'-ribonucleotides (E 635)” Truthinlabeliing.org