# Forum Nature Biotechnology 's Forum podcast explores biotech's latest scientific publications, found in Nature Biotechnology and elsewhere, through discussions with today's leading researchers. Hosted on Acast. See acast.com/privacy for more information. Page: Feed: --- ## [Wearables Roundtable: Bao and Rogers](https://shows.acast.com/forum/episodes/wearables-roundtable-bao-and-rogers) _2025-09-02_ Clinical grade electronic wearable technology today can be flexible, stretchable, and skin-like, as researchers have developed materials that can help electronics interface with your body. Chief Editor Barbara Cheifet speaks with Drs. Zhenan Bao and John Rogers about the many devices that they are working on – from health monitoring in neonates to smart bandages for wounds – and how they will… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/687a560381b46e59569234be/media.mp3) ## [Photoacoustic Imaging Roundtable: Ntziachristos and Yao](https://shows.acast.com/forum/episodes/photoacousticimaging) _2025-08-19_ Photoacoustic imaging, or optoacoustic imaging, combines both optical imaging and ultrasound technology to generate high-resolution images of biological tissues. Chief Editor Barbara Cheifet speaks with Drs. Vasilis Ntziachristos and Junjie Yao about how photoacoustic imaging, developed back in the 1970s, is now moving towards translational applications such as diagnostics and disease monitoring.… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/68714aaeea74e132fbf705f9/media.mp3) ## [Biomolecular Ultrasound Roundtable: Maresca and Shapiro](https://shows.acast.com/forum/episodes/biomolecular-ultrasound) _2025-08-05_ Biomolecular ultrasound is an exciting technology that uses sound waves to visualize tissues within the body. Chief Editor Barbara Cheifet speaks with Drs. David Maresca and Mikhail Shapiro about using ultrasound for imaging and also how the technology is being used to drive the transport of engineered molecules across cellular membranes for a wide range of applications. This includes their recent… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/6871458d610560d3ef5d861f/media.mp3) ## [Foundation Models Roundtable: Lopez and Hie](https://shows.acast.com/forum/episodes/foundation-models-roundtable-hie-and-lopez) _2025-07-22_ Foundation models are machine learning models trained on large datasets and applicable for a wide range of use cases. Chief Editor Barbara Cheifet speaks with Drs. Brian Hie and Marie Lopez about how these models are being used for analysis of the function and structure of DNA, RNA, and proteins, and how they are being developed for clinical use. Hosted on Acast. See acast.com/privacy for more… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/687143ba610560d3ef5cf37d/media.mp3) ## [From Bench to Podcast: Ali Shaib](https://shows.acast.com/forum/episodes/from-bench-to-podcast-ali-shaib) _2024-10-03_ In this episode, Associate Editor Cláudia Vilhena sits down with Ali Shaib, the lead author of an exciting new study showcasing expansion microscopy and the visualization of individual protein shapes, using standard laboratory microscopes. Tune in as Ali and Cláudia explore the “accidental” origins of the study, the importance of mentorship and collaboration, and the democratization of… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/66ec1ef3d4cef78b2bef7f86/media.mp3) ## [From Bench to Podcast: Chloe Fishman](https://shows.acast.com/forum/episodes/from-bench-to-podcast-chloe-fishman) _2024-09-23_ On this episode, our Associate Editor Cláudia Vilhena interviews Chloe Fishman, the first author of a great story on a new and versatile tool using recombitrons for bacteriophage gene editing. Join us as Cláudia and Chloe touch bases on the advantages of this tool over existing methods, discuss the relevance of phage therapy on the fight against antimicrobial resistance and share their thoughts on… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/66e8697c7c9429667606e081/media.mp3) ## [From Bench to Podcast: Nicoletta Cieri](https://shows.acast.com/forum/episodes/from-bench-to-podcast-nicoletta-cieri) _2024-08-20_ On this episode, our Associate Editor Cláudia Vilhena interviews Nicoletta Cieri, the first author of a great story on how a devised analytic framework can aid the prevention of post-transplant disease recurrence. Join us as Nicoletta and Cláudia explore the highlights of the story, discuss the future of individualized medicine and touch-bases on future career opportunities following the postdoc… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/668459c5f364c64008dbdd5b/media.mp3) ## [Organoids Roundtable: Lancaster and Pasca](https://shows.acast.com/forum/episodes/organoids-roundtable-lancaster-and-pasca) _2024-06-26_ In this episode of Forum, Chief Editor Barbara Cheifet speaks with Madeline Lancaster and Sergiu Pasca about organoids – cell cultures derived from stem cells and crafted to replicate a particular organ or certain cell types that make up an organ. These two experts in the field discuss neural organoids specifically, and how they are being used to study both basic biology of the brain and their… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/667aeba2da281499ced22fa8/media.mp3) ## [From Bench to Podcast: Sean Johnson](https://shows.acast.com/forum/episodes/from-bench-to-podcast-sean-johnson) _2024-06-14_ On this episode, our Associate Editor Cláudia Vilhena interviews Sean Johnson, the first author of a timely and great story on how to experimentally evaluate the performance of AI-generated enzymes. Sean and Cláudia discussed the timely topic of AI for protein design and the implications for future research, and also touched base on how it was to transition from academia to industry. For those who… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/66586639068f69001297b00f/media.mp3) ## [From Bench to Podcast: Roman Sarrazin-Gendron](https://shows.acast.com/forum/episodes/from-bench-to-podcast-roman-sarrazin-gendron) _2024-06-06_ On this episode of From Bench to Podcast, our Associate Editor Cláudia Vilhena interviews Roman Sarrazin-Gendron, first author of an absolutely incredible story about...videogames! During this informal chat, Roman and Cláudia talked about the behind the scenes of Boderlands Science. They explored the concepts of Citizen Science , Massively Multiplayer Online Video Games, and the impact of… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/6658622634a87000121ed7b3/media.mp3) ## [Meet Claude, an AI assistant (Sponsored)](https://crawlproof.com/a/fK45nK6Jcv23) _2024-06-06 · **Sponsored**_ Chat with Claude at claude.ai — a conversational AI assistant. ## [Neurotech Roundtable: Anikeeva, Courtine, and Bloch](https://shows.acast.com/forum/episodes/neurotech-roundtable-anikeeva-courtine-and-bloch) _2024-05-15_ On this episode, Chief Editor Barbara Cheifet speaks with Polina Anikeeva from MIT, Grégoire Courtine from EPFL, and Jocelyn Bloch, a neurosurgeon at Lausanne University Hospital. These three leaders in the field of neurotechnologies discuss new devices that help us learn how our brain works, implantable brain-computer interfaces that are helping patients with neurological disorders walk again,… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/66435c111ec45a00127f75ad/media.mp3) ## [From Bench to Podcast: He, Jin and Shi](https://shows.acast.com/forum/episodes/from-bench-to-podcast-stories-from-biotech-labs-siyu-he-yinu) _2024-05-01_ In this episode, our Associate Editor Cláudia Vilhena talks with three authors of the method Starfysh, a computational toolbox combining spatial transcriptomics and histology data. During their chat, Siyu, Yinou and Lingling, all at different stages of their academic path, dig into the layers of Starfysh and its relevance for cancer research. They also share the struggles of peer review, the… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/661e87c5daf4c30017744dfb/media.mp3) ## [From Bench to Podcast: Marcus Walker](https://shows.acast.com/forum/episodes/from-bench-to-podcast-stories-from-biotech-labs-marcus-walke) _2024-04-16_ On our very first episode of the new podcast series from Nature Biotechnology, our Associate Editor Cláudia Vilhena interviews Marcus Walker, first author of a fantastic story on engineered bacteria used to stain textiles. With an informal and honest touch, Marcus and Cláudia dive into the behind the scenes of the paper. From the inspiration to combine microbiology and fashion, passing by what… [Listen](https://sphinx.acast.com/p/acast/s/forum/e/66183ecba609c30016495cdf/media.mp3) ## [Protein Design Roundtable: Deane and Grigoryan](https://shows.acast.com/forum/episodes/protein-design-roundtable-deane-and-grigoryan) _2024-02-01_ For our special Focus Issue, Chief Editor Barbara Cheifet talks with Charlotte Deane and Gevorg Grigoryan about applying new machine learning methods to protein structure prediction and protein design. We discuss exciting new technologies and their current and future clinical applications. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/65a6c75a9b536b00171004b9/media.mp3) ## [Super Resolution and Expansion Microscopy Roundtable: Boyden and Danzl](https://shows.acast.com/forum/episodes/super-resolution-and-expansion-microscopy-roundtable) _2023-06-29_ Microscopy methods today are enabling researchers to see small details within cells, previously undetectable by light microscopy. Chief Editor Barbara Cheifet speaks with Drs. Ed Boyden and Johann Danzl about the technological advances and challenges in the fields of super resolution and expansion microscopy. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/64932e8d470c5300110e7a85/media.mp3) ## [Single-cell metabolomics Roundtable: Alexandrov and Le](https://shows.acast.com/forum/episodes/single-cell-metabolomics-roundtable-alexandrov-and-le) _2023-04-26_ Single-cell metabolomics is focused on detecting, understanding, and interpreting metabolites and lipids at single-cell resolution. Theodore Alexandrov and Anne Le discuss recent technical advances in the field with Chief Editor Barbara Cheifet. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/644678d4ba6ab70011323140/media.mp3) ## [Microbiome Roundtable: Fischbach and Mazmanian](https://shows.acast.com/forum/episodes/microbiome-fischbach-and-mazmanian) _2023-03-01_ Chief Editor Barbara Cheifet speaks with Drs. Michael Fischbach and Sarkis Mazmanian about recent work uncovering functional roles for our microbiomes and what is needed to bring microbiome therapies to the clinic. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/63f7a7acd6d59700115432fd/media.mp3) ## [Xenotransplantation Roundtable: Locke and Sykes](https://shows.acast.com/forum/episodes/xenotransplantation-locke-and-sykes) _2022-12-21_ Jayme Locke and Megan Sykes discuss advances in xenotransplantation with Chief Editor Barbara Cheifet, including details of the recent transplants of pig heart and kidney into braindead patients, as well as the questions researchers and clinicians are asking next. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/63a094fab0e1cf00118a7e72/media.mp3) ## [Human Cell Atlas Roundtable: Regev and Teichmann](https://shows.acast.com/forum/episodes/human-cell-atlas-roundtable-regev-and-teichmann) _2022-08-31_ Aviv Regev and Sarah Teichmann talk with Senior Editor Barbara Cheifet about the development and exciting recent progress of the Human Cell Atlas project. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/630e01acab8c4c0012f6f79f/media.mp3) ## [PROTACs Roundtable: Bertozzi and Deshaies](https://shows.acast.com/forum/episodes/protacs-roundtable-bertozzi-and-deshaies) _2022-07-18_ Senior Editor Markus Elsner has a discussion with Ray Deshaies and Carolyn Bertozzi about PROTACs, small molecules that have the potential to treat previously-undruggable targets in clinical applications. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/62c712d93c109c0012149420/media.mp3) ## [Stocks ranked by what execs say (Sponsored)](https://crawlproof.com/a/5H9SDHKoS7Xh) _2022-07-18 · **Sponsored**_ Evidence-backed watchlists from earnings calls and filings, cited to real transcripts—not guesses. ## [3D Genome Roundtable: Pombo and Phillips-Cremins](https://shows.acast.com/forum/episodes/3d-genome-roundtable-phillips-cremins-and-pombo) _2022-05-16_ Ana Pombo and Jennifer Phillips-Cremins talk with senior editor Barbara Cheifet about how new methods to look at the 3D genome are providing insights into the links between genome structure and cellular function. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/628128445133950013117e1d/media.mp3) ## [CRISPR Screening Roundtable: Stegmaier and Doench](https://shows.acast.com/forum/episodes/crispr-tool-roundtable-stegmaier-and-doench) _2022-04-06_ Kimberly Stegmaier and John Doench speak with senior editor Markus Elsner about the history and latest developments in the field of CRISPR screening. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/p/acast/s/forum/e/6244b6382c665d0012a64d07/media.mp3) ## [Drug Delivery Roundtable: Whitehead and Langer](https://play.acast.com/s/forum/drugdeliveryroundtable-langerandwhitehead) _2021-12-08_ Kathryn Whitehead and Robert Langer talk with Senior Editor Markus Elsner about drug delivery methods and their applications within a wide range of therapeutic modalities. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/drugdeliveryroundtable-langerandwhitehead/media.mp3) ## [Gene Therapy Roundtable: High and Kohn](https://play.acast.com/s/forum/genetherapyroundtable-highandkohn) _2021-09-16_ Katherine High and Donald Kohn speak with senior editor Markus Elsner about the latest developments in gene therapy Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/genetherapyroundtable-highandkohn/media.mp3) ## [Hope Lies in Dreams Chapter 1](https://play.acast.com/s/forum/hopeliesindreamschapter1) _2021-09-08_ Stan Crooke is born ⬩ A tenuous existence ⬩ Life with his mother ⬩ The Tech Corner ⬩ Arsenal Tech High School ⬩ Nancy ⬩ Hoodlum ways ⬩ Off to Purdue Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/hopeliesindreamschapter1/media.mp3) ## [Optogenetics Roundtable: Deisseroth and Gradinaru](https://play.acast.com/s/forum/optogeneticsroundtable-deisserothandgradinaru) _2021-05-25_ Karl Deisseroth and Viviana Gradinaru speak with senior editor Markus Elsner about the current state of optogenetics and how it can be used to better understand and treat human disease. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/optogeneticsroundtable-deisserothandgradinaru/media.mp3) ## [Precision Oncology Roundtable: Siu and Mardis](https://play.acast.com/s/forum/precisiononcologyroundtable-mardisandsiu) _2021-03-10_ Lillian Siu and Elaine Mardis speak with senior editor Markus Elsner about the current state of precision cancer medicine and what progress the future might hold. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/precisiononcologyroundtable-mardisandsiu/media.mp3) ## [The T cell wars](https://play.acast.com/s/forum/thetcellwars-acasteb69d22b) _2020-11-24_ Nature Biotechnology ’s Irene Jarchum speaks with Michel Sadelain about off-the-shelf CAR-T cells, and discusses a recent paper from Maksim Mamonkin’s group describing a clever strategy to mitigate CAR-T cell rejection. The paper was published in Nature Biotechnology and can be read here . Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/thetcellwars-acasteb69d22b/media.mp3) ## [CRISPR Roundtable: Liu and Doudna](https://play.acast.com/s/forum/crisprroundtable-doudnaandliu) _2020-07-07_ David Liu and Jennifer Doudna talk with our Senior Editor Markus Elsner about the state of the genome editing field and what challenges remain, especially as various therapies are now entering the clinic. This episode is part of Nature Biotechnology ’s Focus issue on CRISPR tools and therapies. Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/crisprroundtable-doudnaandliu/media.mp3) ## [Bioengineered scaffolds repair the uterus in rabbits](https://play.acast.com/s/forum/bioengineeredscaffoldsrepairtheuterusinrabbits) _2020-07-01_ A recent Nature Biotechnology paper from Tony Atala and colleagues at Wake Forest describes the use of bioengineered scaffolds to repair substantial injuries to rabbit uteri, supporting pregnancies and live births. Senior Editor Irene Jarchum discusses this work with Mats Brännström and Mats Hellström, both from Gothenburg University in Sweden. You can read the paper here . Hosted on Acast. See… [Listen](https://sphinx.acast.com/forum/bioengineeredscaffoldsrepairtheuterusinrabbits/media.mp3) ## [8.1% APY Plus Free Stock (Sponsored)](https://crawlproof.com/a/ZBrLTukzNByY) _2020-07-01 · **Sponsored**_ Claim 8.1% APY and up to $1,030 in SK hynix and Nvidia stock. ## [Worms and gut microbes team up to kill corn pest](https://play.acast.com/s/forum/wormsandgutmicrobesteamuptokillcornpest) _2020-05-05_ David Shapiro Ilan talks to Senior Editor Susan Jones about a paper in the May issue where Ricardo Machado and colleagues describe how bacterial symbionts of nematodes are evolved to help these worms kill a devastating crop pest: Western Corn Rootworm. The paper can be read here . Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/wormsandgutmicrobesteamuptokillcornpest/media.mp3) ## [First human trial of engineered T cells](https://play.acast.com/s/forum/firsthumantrialofengineeredtcells) _2020-04-21_ Senior Editor Markus Elsner talks to Alex Marson of UCSF about the significance of a Science paper describing the phase 1 clinical trial of CRISPR-engineered T cells. The work was carried out by Carl June and Edward Stadtmauer from UPenn. Read the paper here . Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/firsthumantrialofengineeredtcells/media.mp3) ## [Repurposing viral immunity to fight cancer](https://play.acast.com/s/forum/repurposingviralimmunitytofightcancer) _2020-02-26_ Senior editor Irene Jarchum talks to Cliona Rooney about a recent paper in which Mark Cobbold and colleagues describe an antibody-mediated strategy to re-target virus-specific T cells against tumors. The paper was published in Nature Biotechnology; it can be read here . Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/repurposingviralimmunitytofightcancer/media.mp3) ## [Molecular mapping of tumor heterogeneity](https://play.acast.com/s/forum/molecularmappingoftumorheterogeneity) _2020-02-11_ Brady Huggett talks with Zemin Zhang about a recent Nature Biotechnology paper detailing the use of spatial transcriptomics in providing new insights into tumor architecture. The work was done by Itai Yanai and co-authors, and the paper can be read here . Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/molecularmappingoftumorheterogeneity/media.mp3) ## [Supercooling extends human liver storage](https://play.acast.com/s/forum/schneebergeronclavien) _2020-01-14_ Senior Editor Irene Jarchum talks to Stefan Schneeberger about the significance of a recent Nature Biotechnology paper describing a sophisticated perfusion machine to keep human livers alive for a week. The work was carried out by Pierre-Alain Clavien and colleagues from ETH Zurich. Read the paper here . Hosted on Acast. See acast.com/privacy for more information. [Listen](https://sphinx.acast.com/forum/schneebergeronclavien/media.mp3)