Why is everything a titration problem; why does the traditional healthcare / research system not solve titration for so many therapies; and why do I always find myself having to do it? Good questions that I won’t answer (because I can’t), but it is a good introduction into what I have been working on. I [ ]
Reader, I bought longer shorts. Chafing was my main complaint about wearing an exoskeleton. (Here’s what I got, why I got one, which one I chose, etc. You can also read a second post I wrote about a second version I tried, as well). I got my exoskeleton in July 2025, and now in August [ ]
When you’re diagnosed with celiac disease, it is nice in the sense that you have a known issue (consuming gluten causes an autoimmune reaction and damage to your body) and that the solution is known: eating 100% gluten free. The challenge, though, is that “being gluten free” is not easy. Every food, every drink, every [ ]
Note: I’m assuming if you are reading this post that you’ve first read this post, summarizing the concept. The below is a companion piece with some expanded details about the concepts and more examples of how I think addressing this bottleneck will help make a difference. — You might hold the perspective that in the [ ]
We need more signal, which means we want more noise. A lot of current scientific infrastructure is designed to minimize messiness: define a narrow question, collect the minimum data required to answer it, standardize the dataset, exclude complicating variables, finish the analysis, publish the result. That approach is understandable. It is also one reason we [ ]
I talk a lot about the data we leave behind. A lot of this time, this is in the context of clinical trial design. But more recently, it’s also about the data loss that drives bias in AI. And actually…that same bias exists in humans. And seeking to fix one may also fix the other! [ ]
I thought I would share some of how I am using AI. Previously I’ve talked a lot about broad concepts of prompting LLMs and the types of projects that can be done. I’ve provided particular examples that I’ve found useful for n=1 custom software (to address software-shaped feelings, often) or for improving n=1*many software like [ ]
I have to ask myself these days, is this a software-shaped feeling? This is a riff on something I see online more and more frequently, where people comment about recognizing if this is a “software-shaped problem”. Meaning, is this something that can be solved with software? More recently, this often means n=1 custom, boutique software [ ]
I’ve had a quote in the signature of my email for oh, something like 20 years. It says “Doing something for someone else is better than anything you could do for yourself.” I discovered this a few months after I was diagnosed with type 1 diabetes. It sucked, I was miserable, even though I was [ ]
What if you could stop the spread of infection once it arrives at your house? This is easier to do now than ever before in the era of wearables like smart watches and smart rings that gather biometric data every day and help you learn what your baseline is, making it easier to spot when [ ]