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CXOTalk

C-Suite Conversations on AI and Strategy. Join industry analyst Michael Krigsman for unfiltered discussions with the leaders shaping the future of business. From AI implementation to digital transformation, hear directly from CIOs, CTOs, CEOs, and more from the world's largest companies. No scripts. No PR fluff. Just real questions from our live audience and honest answers from the C-Suite. Want to participate? Get invited to the next live show: https://www.cxotalk.com/subscribe

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Enterprise AI Biggest Opportunities: A Top VC's Take

Enterprise AI has moved past experimentation and now has to prove its return. Ed Sim, Founder and General Partner of boldstart ventures, ranked the No. 1 seed investor in the Business Insider Seed 100 two years running, sees hundreds of AI startup pitches a year, and writes the first check into companies enterprises buy from years later. He wrote the first check into Snyk and backed Protect AI,…

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Why Your Enterprise AI Pilot Won't Scale (with Nate B. Jones)

Most enterprise AI pilots stall or fail before production, and the blocker is rarely the model. Nate B. Jones, an AI analyst and advisor who works with Fortune 500 companies and global banks, tells Michael Krigsman that naming an effort a pilot invites small budgets and safe goals. He explains how to pick a first project that matters to the business, why adoption is roughly 80 percent a people…

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AI Agents in Banking: UBS Former Chief Information Officer

Are AI agents ready for banking and financial services? Former UBS Group CIO Oliver Bussmann explains the risks to trust and reputation in banking. This session examines the current adoption landscape of AI agents within the financial sector. With roughly 50% of financial institutions now integrating these tools into their workflows, understanding the operational implications is critical for…

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Palo Alto Networks EVP: Securing AI Agents in the Enterprise

Enterprises are running more AI agents than their security teams realize, and attackers only need to be right once. Anand Oswal, EVP of Network Security at Palo Alto Networks, explains how to secure agents across four surfaces: enterprise, SaaS, endpoints, and the browser. With host Michael Krigsman, he covers shadow agent discovery, MCP and browser risks, prompt injection, agent identity, and why…

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The CIO Agenda for AI (with IBM Consulting)

CIOs are accountable for AI results but often not in control of how AI is actually used across the business. Andy Baldwin, Senior Vice President of Consulting Offerings and Growth at IBM Consulting, explains how CIOs regain visibility and control as AI moves from small pilots to industrial scale. He describes the real cost of scaling AI, right-sizing models to cut token cost, governance and…

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Eric Ries: Can AI Startups Stay Ethical?

Can AI startups keep their promise to benefit humanity? Eric Ries explains why business success often leads to corporate "corruption" of the founder's mission. Eric Ries, creator of the Lean Startup Method, breaks down the inherent tensions between scaling a business and maintaining its core purpose. We examine why so many organizations lose sight of their initial mission as they grow, and what it…

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McKinsey: Why Agentic AI Pilots Stall

Fewer than 100 companies have scaled enterprise AI from pilots to production to capture great value. Alexander Sukharevsky, who leads QuantumBlack, McKinsey's AI practice, joins Michael Krigsman to lay out the repeatable recipe behind those results and why the winners earn roughly three dollars back for every dollar invested. The conversation covers what capturing AI value really requires, why the…

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Aaron Levie, Box CEO: Advice for CIOs on AI Agents

Agentic AI has taken off in software engineering, but most CIOs still cannot make agents work in everyday knowledge work in the enterprise. Aaron Levie, co-founder and CEO of Box, explains why that gap exists and what enterprises must change to close it. Drawing on what Box sees across its enterprise customer base, including 68% of the Fortune 500, Levie covers data access, verification, budgets,…

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Mozilla CTO: Why Most Enterprises Don't Control Their AI

Most enterprises are renters, not owners, of their technology and AI. Raffi Krikorian, Chief Technology Officer of Mozilla, explains why dependence on a handful of closed model providers means losing control over model behavior, pricing, and your own data. In CXOTalk episode 920, Krikorian lays out where open-source AI actually wins in the enterprise, how lock-in happens quietly, and what CIOs and…

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Enterprise AI: Shadow AI and Agentic Risk - CIO advice

AI agents are entering enterprise AI faster than CIOs can govern them. Line-of-business users are vibe-coding their own tools, agents are operating with employee credentials, and foundation models are changing under running systems. In CXOTalk episode 919, Anthony Scriffignano, PhD, a prominent data scientist, and Tim Crawford, a strategic advisor to CIOs at the world's largest companies, examine…

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