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Cold Spring Harbor Laboratory

Founded in 1890, Cold Spring Harbor Laboratory (CSHL) is a preeminent international research institution, achieving breakthroughs in molecular biology and genetics and enhancing scientific knowledge worldwide.

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Does your immune system learn like AI?

Could AI hold the key to answering questions that have stumped doctors and scientists for decades? A recent study at Cold Spring Harbor Laboratory (CSHL) borrows concepts from machine learning to address an age-old riddle of immunology. In the thymus, the immune system’s T cells are trained to avoid attacking healthy tissue via a process... The post Does your immune system learn like AI? appeared…

New brain map links mice and primates

Most neuroscience research still runs on mice, even though much of what applies to mice does not hold up in humans. Marmosets have emerged as a bridge between species. However, comparing the brains of mice and marmosets runs into a chicken-and-egg problem. Scientists need to know which part of one brain matches the respective region... The post New brain map links mice and primates appeared first…

This is what 945 years of scientific discovery looks like

When visitors tour Cold Spring Harbor Laboratory (CSHL), they often leave inspired by its Nobel Prize–studded legacy, pioneering discoveries, and state-of-the-art facilities humming with cutting-edge research. What they might not see is the community of people working behind the scenes to make every experiment, conference, meal, and every day on campus possible. At the 2026... The post This is…

Cold Spring Harbor Laboratory and Northwell Health lead international cohort of researchers to develop more than 150 next-generation cancer treatment models

Human Cancer Model Initiative releases compendium results of decade-long project to create cancer organoids Ten years and thousands of patient samples later, the National Cancer Institute (NCI) has just published its results from the Human Cancer Model Initiative (HCMI) on the development of 665 organoid models of 25 types of cancer that are now available... The post Cold Spring Harbor Laboratory…

A tale of two neuromodulators

Inside a small enclosure, a mother mouse hears her lost pups crying. She swivels her head to look for the first baby, then darts over to retrieve it. With the distraught pup in her mouth, she scurries back to her nest. Moments later, she rushes to rescue the next one, repeating the process until all... The post A tale of two neuromodulators appeared first on Cold Spring Harbor Laboratory .

Sea to Seed: Spring at CSHL

Science and art aren’t mutually exclusive. Look beyond common anecdotes and misconceptions—like, for example, the whole left brain/right brain debate—and you’ll find a surprising amount of overlap. Cold Spring Harbor Laboratory (CSHL) has long espoused the idea that scientists surrounded by creative works of art will, in turn, be more creative in their science. But... The post Sea to Seed: Spring…

A secret weapon against superbugs

Antibiotic resistance has quietly become one of the greatest threats to global healthcare. Each year, drug-resistant bacteria claim lives by rendering once-reliable antibiotics ineffective, turning routine surgeries, cancer treatments, and even common infections into potentially life-threatening events. Scientists around the world are racing to find new ways to stay ahead of these evolving…

Born of curiosity, CSHL Fellows Program marks 40 years

Long before a scientist wins a Nobel Prize, develops an FDA-approved medicine, or makes a breakthrough discovery, she asks a question. Often, it’s one no one else thinks is worth asking. For 40 years, the Cynthia R. Stebbins Fellows Program at Cold Spring Harbor Laboratory (CSHL) has been built around such curiosity. Unlike traditional postdoctoral... The post Born of curiosity, CSHL Fellows…

CSHL’s 2026 Golf Tournament raises more than $650,000

Cold Spring Harbor Laboratory (CSHL) proudly welcomed more than 280 golfers to its 32nd Annual Golf Tournament on Tuesday, June 16, 2026, at Piping Rock Country Club and The Creek Club. Thanks to a sold-out, double-course tournament, along with spirited participation in the day’s raffles and live auction, the event raised more than $650,000 in... The post CSHL’s 2026 Golf Tournament raises more…

Aspiring physician-scientist to investigate glioblastoma

In a statement, Northwell Health announced that Ethan Ertel, an M.D./Ph.D. student from the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, will join Cold Spring Harbor Laboratory (CSHL) and Northwell teams researching glioblastoma. Ertel will contribute to collaborative laboratory research overseen by CSHL Professor Alea Mills and Northwell’s John Boockvar. The graduate…