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Clinical Significance

Healthcare's intersections with economics, technology, philosophy, statistics, and more.

clinicalsignificance.substack.comSource feed ↗10 episodes

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Latest episodes

Side questing as a doctor, premed curriculums

2026-03

Skills that compound, thoughts on excellence, and the definition of reasoning

2026-02

Most disease are extreme versions of healthy variation

We are in a gold rush to determine the upper and lower bounds of health

The start of something new: Healthcare stakeholders, future physicians, and missed diagnoses

2026-01

When is independence day?

Shortcomings in modern medical training

A broken clock is right twice a day, but is a working clock right all the time?

Reflections on reliability in medical practice

Consensus based medicine shoots for parity and lands at mediocrity

Intelligence can only be leveraged when we encourage independent thinking

Is Medical School a Rational Choice in the Age of AGI?

I’m incredibly excited to start medical school, but some people think I’m making a huge mistake. Who’s right?

Adding Support Where It’s Actually Needed

The future of medical decision making in situations of uncertainty

Healthcare Needs Its Cursor Moment

Innovation always hits a wall when technology isn't easy to use