New scientific developments are transforming the future of cancer treatment and care. Hosted by world-renowned medical oncologist Dr. Manish Shah, CancerCast is your window into research breakthroughs, innovative therapies, and honest accounts of living with and beyond cancer.
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The American Society of Clinical Oncology, or ASCO, Annual Meeting is the world’s largest oncology conference. The meeting brings together cancer experts, thought leaders and professionals from around the world to present groundbreaking research that is changing patient care and moving the field forward. Drs. Manish Shah and David Nanus discuss some of the most impactful research presented at the…
Thanks to advances in cancer care, more people are living longer after a cancer diagnosis than ever before. People are also being diagnosed at earlier ages, leading to an increased number of cancer survivors worldwide. In this episode of CancerCast, Dr. Manish Shah speaks with Dr. Emily Tonorezos about the growing field of cancer survivorship and what it means to live well after a cancer…
As we age, our blood cells naturally develop mutations. With new sequencing technology, we can now identify very rare and specific mutations in human blood more easily and precisely than ever before. It’s like we now have a path to find the needle in a haystack. Researchers have discovered that some of these age-related blood mutations, collectively known as clonal hematopoiesis, may be linked to…
Lung cancer care is changing rapidly and new advances in surgery and medicine are at the forefront. In this episode of CancerCast, Dr. Manish Shah is joined by two lung cancer experts, Drs. Jonathan Villena and Christine Garcia, to explore how innovations in surgery, biomarker testing, targeted therapy, and immunotherapy are transforming outcomes for patients with lung cancer. The conversation…
Bispecific T-cell engager, or BiTE, therapy is an immunotherapy approach that helps the body’s own immune system target cancer cells by bringing immune cells and cancer cells together. In this episode of CancerCast, Dr. Manish Shah is joined by Dr. Mateo Mejia to explain how this form of antibody-based treatment works by directly connecting T cells and cancer cells. It is a new treatment in the…
Prostate-specific membrane antigen, or PSMA, is a protein expressed on the surface of prostate cancer cells that has become an important target for both diagnosing and treating the disease. In this episode of CancerCast, Dr. Manish Shah speaks with prostate cancer expert Dr. Scott Tagawa about how this PSMA protein helps identify whether prostate cancer is confined to the prostate or has spread,…
Discover how liver cancer treatment is evolving in this episode of CancerCast. Dr. Manish Shah and Dr. Juan Rocca discuss the liver’s complicated and critical role in cancer care, from its position as a hotspot for metastasis to the role of the liver in impacting how well certain immunotherapy, chemotherapy and other cancer therapies will work. They explore the newest and most cutting-edge…
In this episode of CancerCast, Dr. Manish Shah is joined by Drs. Gail Roboz and Rick Furman, two internationally renowned Weill Cornell leaders in advancing therapies for leukemia and lymphoma, to preview groundbreaking research from the 2025 American Society of Hematology (ASH) Annual Meeting. Drs. Roboz and Furman highlight some of the most impactful abstracts to be presented during the meeting,…
A liquid biopsy is a blood test that looks for cancer cells or genetic material, such as DNA, that are shed into the bloodstream in patients with cancer. In this episode of CancerCast, Dr. Massimo Cristofanilli and Dr. Manish Shah explore how liquid biopsies unlock real-time insights into cancer evolution through molecular diagnostics, painting a more comprehensive and holistic picture of what’s…
Mismatch repair deficiency is a condition caused by DNA errors in the body that lead to a high number of mutations, increasing cancer risk. Mismatch repair deficiency is also commonly associated with Lynch syndrome, an inherited genetic syndrome linked to higher rates of many cancers at younger ages, including colon cancer. In this episode of CancerCast, Dr. Manish Shah is joined by two guests,…
