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The CLA's Longevity Review

A monthly review of the most interesting and important publications in the field of longevity, from basic science to lifestyle and supplements, as well as the latest news from the Canadian Longevity Association.

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March 2025 Longevity Review

As the flowers are finally starting to bloom in my garden, we will take a look at an intriguing study which uses ultrasound to reverse cellular senescence and increase mouse lifespan; two studies on reducing lower back pain, the first using epigenetic reprogramming, while the second is a Canadian study using senolytics; and, a fascinating study where an induced torpor like state (akin to…

February 2025 Longevity Review

As we emerge from the depth of winter, this month we will take a look at how the combination of Omega 3, Vitamin D and resistance exercise can slow down the aging process; how young blood plasma can help with surgical outcomes in a human trial; how Klotho gene therapy can increase the lifespan of mice; and in the Canadian content study, how cellular reprogramming can protect retinal neurons and…

January 2025 Longevity Review

Kicking off the new year with a lifespan special, we will take a look at reversing the senescence of senescent cells to increase mouse lifespan; the discovery and beneficial effects of a subset of youthful stem cells which can also increase mouse longevity; the most comprehensive study of life-extending molecules in the roundworm

December 2024 Longevity Review

Hello and welcome to the final longevity review of 2024.

November 2024 Longevity Review

As we get closer to the holiday season, this review returns to its monthly format after a brief foray into a bi-monthly issue.

September & October 2024 Longevity Review Part 2

In a bid to finally catch up with these Longevity Reviews, I took the decision to combine the results for September and October.

September & October 2024 Longevity Review Part 1

In a bid to finally catch up with these Longevity Reviews, I took the decision to combine the results for September and October.

August 2024 Longevity Review

Hello again!

July 2024 Longevity Review

Entering the height of the summer, as soon as I post this newsletter and video, I’m going to be taking a couple of weeks off from all things longevity for the first time in more than five years.

June 2024 Longevity Review

With summer in full swing, we will take a look at how early Alzheimer’s could be slowed, stopped or even reversed through extensive lifestyle changes; how CRISPR gene therapy could be used to repair damaged organs; the first lifespan study of NMN; a look at Longevity Summit Dublin; and, how natural antioxidants could prevent the loss of testosterone in older men in the Canadian Content Study.

May 2024 Longevity Review

As we transition towards summer you will find in this month’s Longevity Review, a study showing that senolytics might already be in widespread use; further proof of the mortality benefits of the Mediterranean diet; a Canadian study showing how increased protein intake boosts muscle building in the elderly; news from a longevity conference and a heavyweight debate on the path forward for longevity.

April 2024 Longevity Review

In this month’s Longevity Review you will find how small extracellular vesicles, which cells use to communicate with each other, can increase lifespan in mice; how stem cells taken from umbilical cords can help with frailty in humans; the best time of day to exercise to reduce your mortality if you suffer from obesity or diabetes; and, in the Canadian Content section, how the nuclear envelope is…

March 2024 Longevity Review

As winter enters the rearview mirror, March’s highlights included three lifespan extending studies involving young blood plasma, a two drug synergistic combo and the main bioactive molecule found in mushrooms, and the Canadian content section returns with a groundbreaking study leveraging the powers of AI for drug development.

February 2024 Longevity Review

As we get past the heart of winter, this month we will take a look at how partial reprogramming extends the remaining lifespan of old naturally aged mice; how the Fasting Mimicking Diet reduces biological age; a comparison of intermittent versus continuous dosing of rapamycin in mice; and, a human senolytic trial which raises some concerning questions.

January 2024 Longevity Review

Kicking off the new year with a bevy of interesting longevity research including the intriguing possibility of lifelong protection against senescent cells, harnessing the immune system’s pathogen response to treat ageing, using rapamycin to encourage hair growth, and, in a new addition focusing on Canadian researchers working on longevity, a novel compound which shows potential to rapidly reverse…

November 2023 Longevity Review

This review was a few sentences and an intro away from being finished a few weeks ago before the drama of needing to get a last minute passport derailed my ambitions.

December 2023 Longevity Review

As we wrapped up the year and took a well deserved holiday break, the longevity studies kept on coming.

October 2023 Longevity Review

Hello and welcome again to this month’s longevity review.

September 2023 Longevity Review

Welcome to another Longevity Review.

August 2023 Longevity Review

The dog days of summer might not have been conducive for productivity, but that didn’t stop plenty of longevity studies being published.