Following yesterday's Grok 4.6 release, we ran it against our short-horizon biology tasks on benchmarks.bio. Across 1716 trajectories we generated, we find that Grok 4.6 sits roughly at Opus 5/GPT-Sol-5.6 level of intelligence while being far cheaper.
A few days ago Mistral released Shieldstral, its new safety classifier, without disclosing its performance on major biosecurity related tasks, such as viral engineering.
Today we released results for Kimi-K3, an open-source LLM boasting GPT-5.6/Mythos-level coding-benchmark scores, across our short-horizon therapeutics and -omics benchmarks on benchmarks.bio.
In current generation models, behavioral priors introduce by harnesses such as Claude Code, and Codex cause substantial performance swings on our benchmarks.
A verifiable benchmark for practical decisions about taxonomy, variants, AMR, source tracking, anomaly detection, and engineered sequences in pathogen genomic surveillance workflows.
Two rounds of independent expert attempts define a verified subset of 115 spatial biology tasks and expose ambiguity in benchmark specification and grading.
Biology will not jump straight to autonomous AI scientists. Like software, it will first accelerate where work is executable, feedback-rich, and economically bottlenecked: data analysis.
Overall accuracy for GPT-5.5 and Opus 4.7 remains flat on SpatialBench. Scientist-reviewed trajectories reveal persistent gaps in assay-aware biological judgment.
first contribution towards a broader family of benchmarks spanning major data types // 146 verifiable problems spanning 5 spatial platforms and 7 task categories