Science, Cooperation and Impact in Uncertain Times

In a year marked by geopolitical instability and climate-related health threats, ISGlobal generated evidence for action and strengthened its societal impact. [The following text is the foreword to ISGlobal's 2025 Annual Report , written jointly by Quique Bassat , Director General, and Denise Naniche , Scientific Director.] 2025 was a year of intense geopolitical tension , eroding the…