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exeval provides a reproducible workflow for external evaluation of population pharmacokinetic (popPK) and pharmacokinetic-pharmacodynamic (PKPD) models using independent validation datasets. MAP estimation is currently powered by mapbayr.

The package supports model-informed evaluation workflows based on:

  • Maximum a posteriori (MAP) estimation via mapbayr
  • posterior model updating
  • a priori and Bayesian forecasting simulations
  • predictive performance metrics
  • model comparison across candidate models
  • graphical diagnostics and fit screening

Models can be supplied as:

  • mrgsolve model code (mrgsolve)
  • compiled mrgmod objects
  • built-in curated models included in exeval

Input datasets should follow standard pharmacometric event-table structure (e.g. ID, TIME, DV, AMT, EVID, CMT, OCC), with helper functions available for data preparation.

Installation

You can install the development version of exeval from GitHub with:

install.packages("devtools")
devtools::install_github("Martin-Umpierrez/exeval")

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