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a16z Build Newsletter · Aug 13, 2026

Open roles at Cursor, Town, Replit, and Harvey

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Dani Grant, Katie Kirsch · a16z Jobs

Get on the ground floor with the founding team of a pre-seed or seed-stage startup.

  • Paul Cohen (prev One Medical) and Gil Shklarski (prev CTO at Flatiron Health) are building a new healthcare institution for the next era of medicine. They’re hiring a Design Leader in NYC to invent the design language for human & agentic care, spanning clinician and patient interfaces, digital and in-person. Apply here!

  • Kexin Huang (Stanford CS PhD) and Yuanhao Qu (Stanford Cancer Bio PhD) are building Phylo, a research lab advancing AI biomedical discovery. They’re hiring a Forward Deployed Scientist for up to $275K (South SF) to work directly with pharma and biotech teams. Apply here!

  • The team behind vLLM is building Inferact to make open models cheaper and faster to run. They’re hiring a Founding Product Designer (SF) to define how vLLM and Inferact look and feel. Apply here!

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Inferact CEO Simon Mo says open and closed models are converging. The moat is environment: "What really differentiates open-weight models from closed-weight models? In the end, there's not much differentiation. It's more about the distribution strategy and go-to-market strategy.

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Christian Catalini @ccatalini

Frontier labs argue distillation threatens R&D and US national security. Open-weights proponents counter that diffusion is essential to competition and innovation. Both believe theirs is the only safe path. Luckily, the economics is loyal to neither.

4:34 PM · Aug 11, 2026 · 34.5K Views

16 Replies · 9 Reposts · 110 Likes

  • Nicole Orsak (prev Uber, Stanford) and Rugi (prev Amazon, NVIDIA) are building Tenera (backed by a16z speedrun) to predict how users react to software before you ship it. They’re hiring a Founding Engineer (SF) right now to own features end to end across agent infrastructure, backend, and frontend. Apply here!

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Accelerate the growth of a Series A, B, or C startup with early momentum.

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Join a growth-stage startup scaling to its next horizon.

Our a16z New Media team is hosting an evening of food, drinks, and conversation for new media & social creators on Thurs, August 20th at our SF HQ. RSVP here if you’re interested! (Psst – we’re hiring engineers, designers, marketers, and video/podcast producers.)

This newsletter is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Furthermore, this content is not investment advice, nor is it intended for use by any investors or prospective investors in any a16z funds. This newsletter may link to other websites or contain other information obtained from third-party sources - a16z has not independently verified nor makes any representations about the current or enduring accuracy of such information. If this content includes third-party advertisements, a16z has not reviewed such advertisements and does not endorse any advertising content or related companies contained therein. Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z; visit https://a16z.com/investment-list/ for a full list of investments. Other important information can be found at a16z.com/disclosures. You’re receiving this newsletter since you opted in earlier; if you would like to opt out of future newsletters you may unsubscribe immediately.

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