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1. Among a large cohort of breast cancer survivors, those who participated in digital mental health treatment reported a reduction in symptoms of anxiety, with additional human coaching associated with a reduction in depression. Evidence Rating Level: 1 (Excellent) Almost 50% of all women suffering from advanced breast cancer experience significant anxiety and depression within […] The post A…
1. In a multicenter, single-blind, randomized clinical trial, participation in a cognitive rehabilitation program improved goal attainment and cognitive test scores in patients suffering from Long COVID-related cognitive dysfunction. Evidence Rating Level: 1 (Excellent) Long COVID is defined as a chronic condition that occurs following the infection of COVID-19, present for at least 3 months […]…
1. Among a Danish population-based cohort study, increased initiation of psychotropic medication in the first year following both medical and procedural methods of abortion were found, with decreased risk of initiation of psychotropic medication within five or more years following both medical and procedural abortions. Evidence Rating Level: 2 (Good) There is limited research on […] The post…
1. University of Florida researchers found that glucosamine, the popular joint supplement taken by tens of millions of older Americans, is associated with a 25% higher likelihood of progressing from mild cognitive impairment to Alzheimer’s disease. 2. The proposed mechanism is biochemically plausible: glucosamine is a sugar-related molecule that crosses the blood-brain barrier and appears […] The…
1. H3-10353, a novel γ-aminobutyric acid (GABA) positive allosteric modulator, is safe and well-tolerated in healthy patients and those with major depressive disorder (MDD), and demonstrated some therapeutic benefits in a phase 1 clinical trial. Evidence Rating Level: 1 (Excellent) Although there are numerous classes of medications for depression, these treatments result in remission in […] The…
1. Initiation of centrally acting analgesics in patients with osteoarthritis (OA) was associated with a higher long-term risk of total joint arthroplasty compared with SSRI initiation. 2. Management of comorbid depression may play an important role in OA symptom progression and surgical outcomes, potentially exceeding the benefit of centrally mediated analgesic effects alone. Evidence Rating […]…
1. Genotype-guided prescribing of selective serotonin reuptake inhibitors (SSRIs) may improve treatment response in children and adults with depression. Evidence Rating Level: 1 (Excellent) Although SSRIs are the most prescribed pharmacotherapy for depression, discontinuation rates remain high, with some studies reporting up to 50% discontinuation due to ineffectiveness or adverse effects.…
1. Maternal use of benzodiazepines or non-benzodiazepine hypnotics (Z-hypnotics) during pregnancy was not associated with an increased risk of psychiatric disorders in offspring after controlling for shared familial factors. Evidence Rating Level: 2 (Good) Benzodiazepines and non-benzodiazepine hypnotics (Z-hypnotics) are frequently prescribed drugs among pregnant women who commonly experience…
1. Five days of accelerated continuous theta burst stimulation (a-cTBS) targeting the left primary motor cortex improved social communication impairment in children with autism spectrum disorder. Evidence Rating Level: 1 (Excellent) Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neurostimulation technique that has shown efficacy in treating various neuropsychiatric…
1. The World Health Organization has launched a global initiative to reduce the 15-to-20-year mortality gap for individuals with schizophrenia by 2030. 2. This effort prioritizes the integration of mandatory cardiovascular and metabolic screenings into psychiatric care to treat preventable physical conditions. The World Health Organization and Psychiatric Times have brought renewed attention this…
